Postprandial Triglyceride, Glucose and Insulin Levels 10 Years After Bariatric Surgery in Women With Severe Obesity – A Pilot Study: Part 1 – Laparoscopic Greater Curvature Plication

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023761%3A_____%2F23%3AN0000021" target="_blank" >RIV/00023761:_____/23:N0000021 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/23:10473513

Výsledek na webu

<a href="https://doi.org/10.33549/physiolres.935145" target="_blank" >https://doi.org/10.33549/physiolres.935145</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.33549/physiolres.935145" target="_blank" >10.33549/physiolres.935145</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Postprandial Triglyceride, Glucose and Insulin Levels 10 Years After Bariatric Surgery in Women With Severe Obesity – A Pilot Study: Part 1 – Laparoscopic Greater Curvature Plication

Popis výsledku v původním jazyce

The long-term effects of bariatric surgery on postprandial profiles in patients with obesity and type 2 diabetes (T2D) have not yet been investigated. Therefore, this study examined postprandial profiles before laparoscopic greater curvature plication (LGCP), and then at 2 and 10 years after surgery. The studied cohort included 10 women (mean age= 54.4 +/- 5 years) with obesity (mean BMI= 42.5 +/- 7.8 kg/m(2)) and T2D who underwent LGCP. All subjects underwent a standardized liquid mixed-meal test. For statistical evaluation, ANOVA with Bonferroni multiple comparison was used. Mean postprandial levels were significantly decreased 2 years after surgery. Responses 10 years after the surgery also remained significantly lower than before surgery. Changes observed during the follow-up were significant: glucose: F=34.5, p<0.001; insulin: F=49.3, p<0.001; triglycerides F=9.2, p<0.001. The long-term favorable effects of bariatric surgery on cardiometabolic health may be partly mediated by reductions in postprandial glucose, insulin, and triglyceride levels.

Název v anglickém jazyce

Postprandial Triglyceride, Glucose and Insulin Levels 10 Years After Bariatric Surgery in Women With Severe Obesity – A Pilot Study: Part 1 – Laparoscopic Greater Curvature Plication

Popis výsledku anglicky

The long-term effects of bariatric surgery on postprandial profiles in patients with obesity and type 2 diabetes (T2D) have not yet been investigated. Therefore, this study examined postprandial profiles before laparoscopic greater curvature plication (LGCP), and then at 2 and 10 years after surgery. The studied cohort included 10 women (mean age= 54.4 +/- 5 years) with obesity (mean BMI= 42.5 +/- 7.8 kg/m(2)) and T2D who underwent LGCP. All subjects underwent a standardized liquid mixed-meal test. For statistical evaluation, ANOVA with Bonferroni multiple comparison was used. Mean postprandial levels were significantly decreased 2 years after surgery. Responses 10 years after the surgery also remained significantly lower than before surgery. Changes observed during the follow-up were significant: glucose: F=34.5, p<0.001; insulin: F=49.3, p<0.001; triglycerides F=9.2, p<0.001. The long-term favorable effects of bariatric surgery on cardiometabolic health may be partly mediated by reductions in postprandial glucose, insulin, and triglyceride levels.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30202 - Endocrinology and metabolism (including diabetes, hormones)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Physiological Research

ISSN

0862-8408

e-ISSN

0862-8408

Svazek periodika

72

Číslo periodika v rámci svazku

Suppl. 4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

5

Strana od-do

S399-S403

Kód UT WoS článku

001127421100003

EID výsledku v databázi Scopus

2-s2.0-85180420709