Correlation of lipoprotein(a) with the extent of coronary artery disease in patients with established coronary atherosclerosis – gender differences

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F12%3A00006090" target="_blank" >RIV/00023884:_____/12:00006090 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1177/2047487314527849" target="_blank" >http://dx.doi.org/10.1177/2047487314527849</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/2047487314527849" target="_blank" >10.1177/2047487314527849</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Correlation of lipoprotein(a) with the extent of coronary artery disease in patients with established coronary atherosclerosis – gender differences

Popis výsledku v původním jazyce

Study objective: To assess the gender differences in relation of blood lipids and lipoproteins concentrations with the extent of coronary atherosclerosis in patients with established coronary artery disease (CAD). Patients population and methods: Blood lipids and lipoproteins concentrations were measured in 351 consecutive patients (256 men and 95 women) who underwent coronary angiography between January and May 2010, and who had established coronary atherosclerosis (angiography score > 1). A modified angiographic Gensini Score was used. Results: men had lower mean HDL cholesterol level than women (1.05 vs. 1.18 mmol/l), and lower mean apolipoprotein A level (1.41 vs. 1.53 g/l). Mean lipoprotein(a) level was higher in men than women (307.1 vs 282.7 mg/l). Mean angiographic score was 19.6 in men and 15.0 in women. Significant inverse correlation between HDL chol and apoA with angiographic score was identified in women (r = - 0,23, p = 0,028 and r = - 0.26, p = 0,025), but not in men. Lipoprotein(a) level correlated significantly with angiographic score only in men (r = 0.168, p = 0.0185). Conclusion: Gender differences were identified in patients with established coronary atherosclerosis in the relation of blood lipids and lipoproteins with the extent of coronary artery disease.

Název v anglickém jazyce

Correlation of lipoprotein(a) with the extent of coronary artery disease in patients with established coronary atherosclerosis – gender differences

Popis výsledku anglicky

Study objective: To assess the gender differences in relation of blood lipids and lipoproteins concentrations with the extent of coronary atherosclerosis in patients with established coronary artery disease (CAD). Patients population and methods: Blood lipids and lipoproteins concentrations were measured in 351 consecutive patients (256 men and 95 women) who underwent coronary angiography between January and May 2010, and who had established coronary atherosclerosis (angiography score > 1). A modified angiographic Gensini Score was used. Results: men had lower mean HDL cholesterol level than women (1.05 vs. 1.18 mmol/l), and lower mean apolipoprotein A level (1.41 vs. 1.53 g/l). Mean lipoprotein(a) level was higher in men than women (307.1 vs 282.7 mg/l). Mean angiographic score was 19.6 in men and 15.0 in women. Significant inverse correlation between HDL chol and apoA with angiographic score was identified in women (r = - 0,23, p = 0,028 and r = - 0.26, p = 0,025), but not in men. Lipoprotein(a) level correlated significantly with angiographic score only in men (r = 0.168, p = 0.0185). Conclusion: Gender differences were identified in patients with established coronary atherosclerosis in the relation of blood lipids and lipoproteins with the extent of coronary artery disease.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Preventive Cardiology

ISSN

2047-4881

e-ISSN

—

Svazek periodika

22

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

3

Strana od-do

603-605

Kód UT WoS článku

000352791900007

EID výsledku v databázi Scopus

2-s2.0-84927634405