Acute effect of spinal cord stimulation on autonomic nervous system function in patients with heart failure

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F21%3A00008953" target="_blank" >RIV/00023884:_____/21:00008953 - isvavai.cz</a>

Výsledek na webu

<a href="https://jab.zsf.jcu.cz/artkey/jab-202103-0002_acute-effect-of-spinal-cord-stimulation-on-autonomic-nervous-system-function-in-patients-with-heart-failure.php" target="_blank" >https://jab.zsf.jcu.cz/artkey/jab-202103-0002_acute-effect-of-spinal-cord-stimulation-on-autonomic-nervous-system-function-in-patients-with-heart-failure.php</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.32725/jab.2021.012" target="_blank" >10.32725/jab.2021.012</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Acute effect of spinal cord stimulation on autonomic nervous system function in patients with heart failure

Popis výsledku v původním jazyce

Aims: To test the hypothesis that spinal cord stimulation (SCS) acutely improves heart rate variability (HRV) and baroreceptor sensitivity (BRS) in patients with heart failure (HF). Methods: SCS (15 minutes) was delivered in four different settings: 90% of maximal tolerated stimulation amplitude (MTA) targeting the T1–T4 spinal cord segments (SCS90T1–4), 60% of MTA (SCS60T1–4), 90% of MTA with cranial (SCS90CR) and caudal (SCS90CA) electrode configuration. HRV and BRS were recorded continuously and stimulation was compared to device off. Results: Fifteen HF patients were included. SCS90T1–4 did not change the standard deviation of intervals between normal beats (SDNN, p = 0.90), BRS (p = 0.55) or other HRV parameters. In patients with baseline SDNN <50 ms, SCS90T1–4 significantly increased SDNN (p = 0.004). Conclusions: Acute SCS at 60–90% of MTA targeting upper thoracic spinal cord segments does not improve autonomic balance or baroreceptor sensitivity in unselected patients with heart failure but may improve HRV in patients with low SDNN.

Název v anglickém jazyce

Acute effect of spinal cord stimulation on autonomic nervous system function in patients with heart failure

Popis výsledku anglicky

Aims: To test the hypothesis that spinal cord stimulation (SCS) acutely improves heart rate variability (HRV) and baroreceptor sensitivity (BRS) in patients with heart failure (HF). Methods: SCS (15 minutes) was delivered in four different settings: 90% of maximal tolerated stimulation amplitude (MTA) targeting the T1–T4 spinal cord segments (SCS90T1–4), 60% of MTA (SCS60T1–4), 90% of MTA with cranial (SCS90CR) and caudal (SCS90CA) electrode configuration. HRV and BRS were recorded continuously and stimulation was compared to device off. Results: Fifteen HF patients were included. SCS90T1–4 did not change the standard deviation of intervals between normal beats (SDNN, p = 0.90), BRS (p = 0.55) or other HRV parameters. In patients with baseline SDNN <50 ms, SCS90T1–4 significantly increased SDNN (p = 0.004). Conclusions: Acute SCS at 60–90% of MTA targeting upper thoracic spinal cord segments does not improve autonomic balance or baroreceptor sensitivity in unselected patients with heart failure but may improve HRV in patients with low SDNN.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal Of Applied Biomedicine

ISSN

1214-021X

e-ISSN

—

Svazek periodika

19

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

133-141

Kód UT WoS článku

000705337500002

EID výsledku v databázi Scopus

2-s2.0-85115743978