Leadless left ventricular endocardial pacing for CRT upgrades in previously failed and high-risk patients in comparison with coronary sinus CRT upgrades

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F21%3A00009117" target="_blank" >RIV/00023884:_____/21:00009117 - isvavai.cz</a>

Výsledek na webu

<a href="https://academic-oup-com.ezproxy.lib.cas.cz/europace/article/23/10/1577/6329891" target="_blank" >https://academic-oup-com.ezproxy.lib.cas.cz/europace/article/23/10/1577/6329891</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/europace/euab156" target="_blank" >10.1093/europace/euab156</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Leadless left ventricular endocardial pacing for CRT upgrades in previously failed and high-risk patients in comparison with coronary sinus CRT upgrades

Popis výsledku v původním jazyce

Aims Cardiac resynchronization therapy (CRT) upgrades may be Less Likely to improve following intervention. Leadless left ventricular (LV) endocardial pacing has been used for patients with previously failed CRT or high-risk upgrades. We compared procedural and long-term outcomes in patients undergoing coronary sinus (CS) CRT upgrades with high-risk and previously failed CRT upgrades undergoing LV endocardial upgrades. Method and results Prospective consecutive CS upgrades between 2015 and 2019 were compared with those undergoing WiSE-CRT implantation. Cardiac resynchronization therapy response at 6 months was defined as improvement in clinical composite score (CCS) and a reduction in LV end-systolic volume (LVESV) >= 15%. A total of 225 patients were analysed; 121 CS and 104 endocardial upgrades. Patients receiving WISE-CRT tended to have more comorbidities and were more likely to have previous cardiac surgery (30.9% vs. 16.5%; P=0.012), hypertension (59.2% vs. 34.7%; P< 0.001), chronic obstructive airways disease (19.4% vs. 9.9%; P=0.046), and chronic kidney disease (46.4% vs. 21.5%; P< 0.01) but similar LV ejection fraction (30.0 +/- 8.3% vs. 29.5 +/- 8.6%; P= 0.678). WiSE-CRT upgrades were successful in 97.1% with procedure-related mortality in 1.9%. Coronary sinus upgrades were successful in 97.5% of cases with a 2.5% rate of CS dissection and 5.6% lead malfunction/displacement. At 6 months, 91 WiSE-CRT upgrades and 107 CS upgrades had similar improvements in CCS (76.3% vs. 68.5%; P= 0.210) and reduction in LVESV >= 15% (54.2% vs. 56.3%; P = 0.835). Conclusion Despite prior failed upgrades and high-risk patients with more comorbidities, WiSE-CRT upgrades had high rates of procedural success and similar improvements in CCS and LV remodelling with CS upgrades.

Název v anglickém jazyce

Leadless left ventricular endocardial pacing for CRT upgrades in previously failed and high-risk patients in comparison with coronary sinus CRT upgrades

Popis výsledku anglicky

Aims Cardiac resynchronization therapy (CRT) upgrades may be Less Likely to improve following intervention. Leadless left ventricular (LV) endocardial pacing has been used for patients with previously failed CRT or high-risk upgrades. We compared procedural and long-term outcomes in patients undergoing coronary sinus (CS) CRT upgrades with high-risk and previously failed CRT upgrades undergoing LV endocardial upgrades. Method and results Prospective consecutive CS upgrades between 2015 and 2019 were compared with those undergoing WiSE-CRT implantation. Cardiac resynchronization therapy response at 6 months was defined as improvement in clinical composite score (CCS) and a reduction in LV end-systolic volume (LVESV) >= 15%. A total of 225 patients were analysed; 121 CS and 104 endocardial upgrades. Patients receiving WISE-CRT tended to have more comorbidities and were more likely to have previous cardiac surgery (30.9% vs. 16.5%; P=0.012), hypertension (59.2% vs. 34.7%; P< 0.001), chronic obstructive airways disease (19.4% vs. 9.9%; P=0.046), and chronic kidney disease (46.4% vs. 21.5%; P< 0.01) but similar LV ejection fraction (30.0 +/- 8.3% vs. 29.5 +/- 8.6%; P= 0.678). WiSE-CRT upgrades were successful in 97.1% with procedure-related mortality in 1.9%. Coronary sinus upgrades were successful in 97.5% of cases with a 2.5% rate of CS dissection and 5.6% lead malfunction/displacement. At 6 months, 91 WiSE-CRT upgrades and 107 CS upgrades had similar improvements in CCS (76.3% vs. 68.5%; P= 0.210) and reduction in LVESV >= 15% (54.2% vs. 56.3%; P = 0.835). Conclusion Despite prior failed upgrades and high-risk patients with more comorbidities, WiSE-CRT upgrades had high rates of procedural success and similar improvements in CCS and LV remodelling with CS upgrades.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

EP Europace

ISSN

1099-5129

e-ISSN

—

Svazek periodika

23

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

1577-1585

Kód UT WoS článku

000713681500009

EID výsledku v databázi Scopus

2-s2.0-85118285828