Effect of sodium-glucose co-transporter-2 inhibitor on estimated plasma volume in a patient with heart failure with reduced ejection fraction and a patient with heart failure with preserved ejection fraction

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F24%3A00009826" target="_blank" >RIV/00023884:_____/24:00009826 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/24:43927331

Výsledek na webu

<a href="https://pubmed.ncbi.nlm.nih.gov/39031990/" target="_blank" >https://pubmed.ncbi.nlm.nih.gov/39031990/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/clc.24303" target="_blank" >10.1002/clc.24303</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effect of sodium-glucose co-transporter-2 inhibitor on estimated plasma volume in a patient with heart failure with reduced ejection fraction and a patient with heart failure with preserved ejection fraction

Popis výsledku v původním jazyce

Background: The increased diuresis after sodium-glucose cotransporter 2 inhibitor (SGLT2i) was associated with a reduction of the estimated plasma volume in type 2 diabetic patients. Hypothesis: We hypothesised that the effect of SGLT2i on estimated plasma volume may be monitored by the change of biomarkers of hemoconcentration. Patients and methods: We analyzed the long term effect of SGLT2i empagliflozin on the estimated plasma volume as assessed by biomarkers of hemoconcentration in a non-diabetic patient with heart failure and reduced ejection fraction (HFrEF) and a non-diabetic pateint with heart failure and preserved ejection fraction (HFpEF). The estimated plasma volume (ePV) was calculated from hemoglobin and hematocrit levels by Duarte formula and ePV change was calculated vy Strauss formula. Results: The ePV change was – 22.56 % between baseline and one month,and – 37.60 % between baseline and 12 months follow-up in a patient with HFrEF, and – 6.18 % and – 16.40 % in a patient with HFpEF respectively. Conclusion: The effect of SGLT2i on estimated plasma volume in patients with heart failure may be monitored by biomarkers of hemoconcentration.

Název v anglickém jazyce

Effect of sodium-glucose co-transporter-2 inhibitor on estimated plasma volume in a patient with heart failure with reduced ejection fraction and a patient with heart failure with preserved ejection fraction

Popis výsledku anglicky

Background: The increased diuresis after sodium-glucose cotransporter 2 inhibitor (SGLT2i) was associated with a reduction of the estimated plasma volume in type 2 diabetic patients. Hypothesis: We hypothesised that the effect of SGLT2i on estimated plasma volume may be monitored by the change of biomarkers of hemoconcentration. Patients and methods: We analyzed the long term effect of SGLT2i empagliflozin on the estimated plasma volume as assessed by biomarkers of hemoconcentration in a non-diabetic patient with heart failure and reduced ejection fraction (HFrEF) and a non-diabetic pateint with heart failure and preserved ejection fraction (HFpEF). The estimated plasma volume (ePV) was calculated from hemoglobin and hematocrit levels by Duarte formula and ePV change was calculated vy Strauss formula. Results: The ePV change was – 22.56 % between baseline and one month,and – 37.60 % between baseline and 12 months follow-up in a patient with HFrEF, and – 6.18 % and – 16.40 % in a patient with HFpEF respectively. Conclusion: The effect of SGLT2i on estimated plasma volume in patients with heart failure may be monitored by biomarkers of hemoconcentration.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Clinical Cardiology

ISSN

0160-9289

e-ISSN

—

Svazek periodika

47

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

—

Kód UT WoS článku

001272213800001

EID výsledku v databázi Scopus

2-s2.0-85198912331