Isobutyrylshikonin and isovalerylshikonin from the roots of Onosma visianii inhibit larval growth of the tobacco cutworm Spodoptera littoralis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027006%3A_____%2F17%3A00004073" target="_blank" >RIV/00027006:_____/17:00004073 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.indcrop.2017.08.048" target="_blank" >http://dx.doi.org/10.1016/j.indcrop.2017.08.048</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.indcrop.2017.08.048" target="_blank" >10.1016/j.indcrop.2017.08.048</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Isobutyrylshikonin and isovalerylshikonin from the roots of Onosma visianii inhibit larval growth of the tobacco cutworm Spodoptera littoralis

Popis výsledku v původním jazyce

In the present work, we evaluated the toxicity and growth inhibitory effects on Spodoptera littoralis (Boisd.) (Lepidoptera: Noctuidae) of the root hexane extract from Onosma visianii (Boraginaceae). Furthermore, two naphtooquinone derivatives, namely isobutyrylshikonin and isovalerylshikonin, which were isolated from the extract by column chromatography and identified by Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) techniques, were also assayed for the same target. The O. visianii extract, at 30.0 µg/cm2, led to 100% mortality at day 7, with LD50 of 6.8 µg/cm2 for the same day. On the other hand, isovalerylshikonin was significantly more effective (LD50 = 0.8 µg/cm2) than isobutyrylshikonin (LD50 = 7.3 µg/cm2). The two tested naphtoquinones inhibited the growth of S. littoralis larvae with ED50 of 0.4 and 0.3 µg/cm2, respectively. Furthermore, isovalerylshikonin provide a stronger inhibition of acetylcholinesterase (AChE) enzyme (IC50 = 51.4 µg/mL), than isobutyrylshikonin (IC50 = 162.0 µg/mL). These findings provided new insights into the potential of shikonin derivatives as new valuable botanical insecticides to be used in crop protection. Isobutyrylshikonin and isovalerylshikonin from the roots of Onosma visianii inhibit larval growth of the tobacco cutworm Spodoptera littoralis.

Název v anglickém jazyce

Isobutyrylshikonin and isovalerylshikonin from the roots of Onosma visianii inhibit larval growth of the tobacco cutworm Spodoptera littoralis

Popis výsledku anglicky

In the present work, we evaluated the toxicity and growth inhibitory effects on Spodoptera littoralis (Boisd.) (Lepidoptera: Noctuidae) of the root hexane extract from Onosma visianii (Boraginaceae). Furthermore, two naphtooquinone derivatives, namely isobutyrylshikonin and isovalerylshikonin, which were isolated from the extract by column chromatography and identified by Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) techniques, were also assayed for the same target. The O. visianii extract, at 30.0 µg/cm2, led to 100% mortality at day 7, with LD50 of 6.8 µg/cm2 for the same day. On the other hand, isovalerylshikonin was significantly more effective (LD50 = 0.8 µg/cm2) than isobutyrylshikonin (LD50 = 7.3 µg/cm2). The two tested naphtoquinones inhibited the growth of S. littoralis larvae with ED50 of 0.4 and 0.3 µg/cm2, respectively. Furthermore, isovalerylshikonin provide a stronger inhibition of acetylcholinesterase (AChE) enzyme (IC50 = 51.4 µg/mL), than isobutyrylshikonin (IC50 = 162.0 µg/mL). These findings provided new insights into the potential of shikonin derivatives as new valuable botanical insecticides to be used in crop protection. Isobutyrylshikonin and isovalerylshikonin from the roots of Onosma visianii inhibit larval growth of the tobacco cutworm Spodoptera littoralis.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40106 - Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Industrial Crops and Products

ISSN

0926-6690

e-ISSN

—

Svazek periodika

109

Číslo periodika v rámci svazku

December

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

266-273

Kód UT WoS článku

000413880300034

EID výsledku v databázi Scopus

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