Phenolic compounds and bioactive properties of Verbascum glabratum subsp. bosnense (K. Malý) Murb., an endemic plant species

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027006%3A_____%2F20%3A10141709" target="_blank" >RIV/00027006:_____/20:10141709 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15310/20:73603733

Výsledek na webu

<a href="https://www.tandfonline.com/doi/abs/10.1080/14786419.2018.1538221" target="_blank" >https://www.tandfonline.com/doi/abs/10.1080/14786419.2018.1538221</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/14786419.2018.1538221" target="_blank" >10.1080/14786419.2018.1538221</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Phenolic compounds and bioactive properties of Verbascum glabratum subsp. bosnense (K. Malý) Murb., an endemic plant species

Popis výsledku v původním jazyce

Detailed analysis of phenolic composition and antioxidant and antimicrobial activities ofVerbascum glabratumsubsp.bosnense(K. Maly) Murb., an endemic species of southeastern Dinaric Alps was performed for the first time. The phenolic composition measured via UHPLC-MS/MS of four extract with different polarity suggested this plant species is very rich in both phenolic acids and flavonoids. Ethanol extract was chemically the most versatile containing 12 compounds with quercitrin and rosmarinic acid as the majors, while water extracts were rich in 4-hydroxybenzoic acid, salicylic acid, morin, and apigenin. All extracts showed high antioxidant potential measured spectrophotometrically with IC(50)values ranging 0.139 - 0.021 mg/mL. Antimicrobial testing using agar diffusion test showed that ethanol extract was the most potent against all tested organisms. Also, these activities are correlated with the content of phenolic compounds, which suggest they are active ingredients of the extracts.

Název v anglickém jazyce

Phenolic compounds and bioactive properties of Verbascum glabratum subsp. bosnense (K. Malý) Murb., an endemic plant species

Popis výsledku anglicky

Detailed analysis of phenolic composition and antioxidant and antimicrobial activities ofVerbascum glabratumsubsp.bosnense(K. Maly) Murb., an endemic species of southeastern Dinaric Alps was performed for the first time. The phenolic composition measured via UHPLC-MS/MS of four extract with different polarity suggested this plant species is very rich in both phenolic acids and flavonoids. Ethanol extract was chemically the most versatile containing 12 compounds with quercitrin and rosmarinic acid as the majors, while water extracts were rich in 4-hydroxybenzoic acid, salicylic acid, morin, and apigenin. All extracts showed high antioxidant potential measured spectrophotometrically with IC(50)values ranging 0.139 - 0.021 mg/mL. Antimicrobial testing using agar diffusion test showed that ethanol extract was the most potent against all tested organisms. Also, these activities are correlated with the content of phenolic compounds, which suggest they are active ingredients of the extracts.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10609 - Biochemical research methods

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

NATURAL PRODUCT RESEARCH

ISSN

1478-6419

e-ISSN

—

Svazek periodika

34

Číslo periodika v rámci svazku

16

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

2407-2411

Kód UT WoS článku

000561132800030

EID výsledku v databázi Scopus

2-s2.0-85059060949