Genetic Variability of Lipogenic Enzymes (DGAT2, SCD) and Glycoprotein (BTN1A1) in the Dairy Goat Population of the Czech Republic

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F16%3AN0000027" target="_blank" >RIV/00027014:_____/16:N0000027 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.vuzv.cz/sites/File/_privat/16026.pdf" target="_blank" >http://www.vuzv.cz/sites/File/_privat/16026.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Genetic Variability of Lipogenic Enzymes (DGAT2, SCD) and Glycoprotein (BTN1A1) in the Dairy Goat Population of the Czech Republic

Popis výsledku v původním jazyce

Enhancing milk productivity, yield and composition are of great economic importance for the dairy goat industry. They are influenced by multiple genes or quantitative loci (QTL) dispersed across the genome, and by an array of different environmental factors. The aim of this study was to investigate the variation/genetic polymorphism in the lipogenic enzymes DGAT2 and SCD and the glycoprotein BTN1A1 in the dairy goat population of the Czech Republic. Typing of the DGAT2, SCD and BTN1A1 loci was performed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Molecular analysis onfirmed the polymorphic site in exon 4 at position 216A > G and revealed that the most prevalent genotype was GG (76.09 percent) followed by AG (21.30 percent) and AA (2.61 percent) at the BTN1A1 locus in the studied goat population. The frequency of allele B (82.24 percent) and genotype BB (71.71 percent) predominated over allele A (14.47 percent) and genotypes AA (1.97 percent), AB (21.05 percent) and AC (3.95 percent), and allele C (3.29 percent) and genotype CC (1.32 percent) in the region of exon 3 and intron 3 at the SCD locus in the studied goat population. No polymorphism was detected in exon 4 at the DGAT2 locus. This information on genotype variability in the dairy goat population could be exploited in breeding programmes aiming to preserve biodiversity or improve the quality of processed milk from Czech goat breeds.

Název v anglickém jazyce

Genetic Variability of Lipogenic Enzymes (DGAT2, SCD) and Glycoprotein (BTN1A1) in the Dairy Goat Population of the Czech Republic

Popis výsledku anglicky

Enhancing milk productivity, yield and composition are of great economic importance for the dairy goat industry. They are influenced by multiple genes or quantitative loci (QTL) dispersed across the genome, and by an array of different environmental factors. The aim of this study was to investigate the variation/genetic polymorphism in the lipogenic enzymes DGAT2 and SCD and the glycoprotein BTN1A1 in the dairy goat population of the Czech Republic. Typing of the DGAT2, SCD and BTN1A1 loci was performed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Molecular analysis onfirmed the polymorphic site in exon 4 at position 216A > G and revealed that the most prevalent genotype was GG (76.09 percent) followed by AG (21.30 percent) and AA (2.61 percent) at the BTN1A1 locus in the studied goat population. The frequency of allele B (82.24 percent) and genotype BB (71.71 percent) predominated over allele A (14.47 percent) and genotypes AA (1.97 percent), AB (21.05 percent) and AC (3.95 percent), and allele C (3.29 percent) and genotype CC (1.32 percent) in the region of exon 3 and intron 3 at the SCD locus in the studied goat population. No polymorphism was detected in exon 4 at the DGAT2 locus. This information on genotype variability in the dairy goat population could be exploited in breeding programmes aiming to preserve biodiversity or improve the quality of processed milk from Czech goat breeds.

Druh

D - Stať ve sborníku

CEP obor

GG - Chov hospodářských zvířat

OECD FORD obor

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Projekt

<a href="/cs/project/QJ1310107" target="_blank" >QJ1310107: Vliv genetického polymorfizmu lipogenických enzymů na složení mléčného tuku a obsah mastných kyselin v mléce malých přežvýkavců (kozy a ovce).</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Sustainable goat breeding and goat farming in the Central and Eastern European Countries

ISBN

978-92-5-109123-4

ISSN

ne

e-ISSN

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Počet stran výsledku

6

Strana od-do

133-138

Název nakladatele

Food and Agriculture Organization of the United Nations

Místo vydání

Rome

Místo konání akce

Rome

Datum konání akce

7. 4. 2014

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

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