The oocyte´s nucleolus precursor body: The globe for life

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F18%3AN0000241" target="_blank" >RIV/00027014:_____/18:N0000241 - isvavai.cz</a>

Výsledek na webu

<a href="https://content.sciendo.com/view/journals/macvetrev/41/2/article-p115.xml" target="_blank" >https://content.sciendo.com/view/journals/macvetrev/41/2/article-p115.xml</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2478/macvetrev-2018-0013" target="_blank" >10.2478/macvetrev-2018-0013</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The oocyte´s nucleolus precursor body: The globe for life

Popis výsledku v původním jazyce

The nucleolus is the cell organelle responsible for ribosome synthesis and, hence, for protein synthesis. In the mammalian oocyte, the nucleolus compacts into a dense sphere with no ribosome synthesis well in advance of ovulation. It seems, that this body is of utmost importance for the development of the embryo. It is unknown, however, how it exerts this essential function. During the last two decades, great attention has been paid to the study of nucleogenesis in oocytes and early embryos, with transcription of ribosomal DNA being evaluated as one of the criteria of normal development. In this review, we summarize some aspects of nucleolus transformation during oocyte growth, as well as during early embryonic development with possible impact on the quality of the embryos used in biomedical research. This knowledge in connection with further observations will substantially contribute to the development of new criteria suitable for evaluation of oocytes and embryos used in biomedical application.

Název v anglickém jazyce

The oocyte´s nucleolus precursor body: The globe for life

Popis výsledku anglicky

The nucleolus is the cell organelle responsible for ribosome synthesis and, hence, for protein synthesis. In the mammalian oocyte, the nucleolus compacts into a dense sphere with no ribosome synthesis well in advance of ovulation. It seems, that this body is of utmost importance for the development of the embryo. It is unknown, however, how it exerts this essential function. During the last two decades, great attention has been paid to the study of nucleogenesis in oocytes and early embryos, with transcription of ribosomal DNA being evaluated as one of the criteria of normal development. In this review, we summarize some aspects of nucleolus transformation during oocyte growth, as well as during early embryonic development with possible impact on the quality of the embryos used in biomedical research. This knowledge in connection with further observations will substantially contribute to the development of new criteria suitable for evaluation of oocytes and embryos used in biomedical application.

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

—

OECD FORD obor

10609 - Biochemical research methods

Projekt

<a href="/cs/project/GA17-08605S" target="_blank" >GA17-08605S: Jaderné a cytoplasmatické determinanty zodpovědné za regulaci zrání oocytů a vývoj embrya</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Macedonian Veterinary Review

ISSN

1409-7621

e-ISSN

—

Svazek periodika

41

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

MK - Republika Severní Makedonie

Počet stran výsledku

8

Strana od-do

115-122

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85068196103