Preparation and Characterization of Hydrophobic and Hydrophilic Amidated Derivatives of Carboxymethyl Chitosan

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F20%3AN0000131" target="_blank" >RIV/00027014:_____/20:N0000131 - isvavai.cz</a>

Výsledek na webu

<a href="https://vuzv.cz/_privat/20128.pdf" target="_blank" >https://vuzv.cz/_privat/20128.pdf</a>

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Preparation and Characterization of Hydrophobic and Hydrophilic Amidated Derivatives of Carboxymethyl Chitosan

Popis výsledku v původním jazyce

Chitosan is substance that is very widely used in the pharmaceutical and food industries, medicine and other areas. This polysaccharide has immense significance in human metabolism. It is able to affect the levels of cholesterol and lipids. Chemical modification of this polysaccharide allows the support of these attributes. A main goal is to prepare a group of amide derivatives of carboxymethyl chitosan to obtain a new group of polysaccharide derivatives and increase the benefits and attributes. The aim of carboxymethylation and subsequent two-step amidation is to achieve a high degree of substitution in the prepared derivatives. The amidation consisted methyl esterification followed by amino-de-alkoxylation with amidation reagents (nalkylamines, hydrazine and hydroxylamine). The purity and substitution degree of the prepared derivatives were monitored by vibration spectroscopic methods (FTIR and FT Raman) and organic elemental analysis.

Název v anglickém jazyce

Preparation and Characterization of Hydrophobic and Hydrophilic Amidated Derivatives of Carboxymethyl Chitosan

Popis výsledku anglicky

Chitosan is substance that is very widely used in the pharmaceutical and food industries, medicine and other areas. This polysaccharide has immense significance in human metabolism. It is able to affect the levels of cholesterol and lipids. Chemical modification of this polysaccharide allows the support of these attributes. A main goal is to prepare a group of amide derivatives of carboxymethyl chitosan to obtain a new group of polysaccharide derivatives and increase the benefits and attributes. The aim of carboxymethylation and subsequent two-step amidation is to achieve a high degree of substitution in the prepared derivatives. The amidation consisted methyl esterification followed by amino-de-alkoxylation with amidation reagents (nalkylamines, hydrazine and hydroxylamine). The purity and substitution degree of the prepared derivatives were monitored by vibration spectroscopic methods (FTIR and FT Raman) and organic elemental analysis.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Proceedings of the 16th International Conference on Polysaccharides-Glycoscience

ISBN

978-80-88307-05-1

ISSN

—

e-ISSN

—

Počet stran výsledku

4

Strana od-do

113-116

Název nakladatele

Česká společnost chemická

Místo vydání

Praha

Místo konání akce

Prague

Datum konání akce

4. 11. 2020

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

000668569900029