Interaction of the ovine host genome with Corynebacterium pseudotuberculosis infection
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F23%3A10005800" target="_blank" >RIV/00027014:_____/23:10005800 - isvavai.cz</a>
Výsledek na webu
<a href="https://vuzv.cz/_privat/23077.pdf" target="_blank" >https://vuzv.cz/_privat/23077.pdf</a>
DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Interaction of the ovine host genome with Corynebacterium pseudotuberculosis infection
Popis výsledku v původním jazyce
Corynebacterium pseudotuberculosis (Cp) is the etiological agent of caseous lymphadenitis, which has a detrimental impact on the health of small ruminants. The study's goals were the characterization of the ovine whole blood transcriptome and functional comparison of the differentially expressed genes between healthy and affected animals. The blood samples of East Frisian sheep were obtained from Cp serologically positive (3) and negative ewes (3) and the health controls (3) of another herd. Differential gene expression was analyzed by RNA-seq on an Illumina NextSeqTM 550 system using the DESeq2 approach. The DEG sets were annotated with UniProt Knowledgebase and the WEB-based GEne SeT AnaLysis Toolkit.
Název v anglickém jazyce
Interaction of the ovine host genome with Corynebacterium pseudotuberculosis infection
Popis výsledku anglicky
Corynebacterium pseudotuberculosis (Cp) is the etiological agent of caseous lymphadenitis, which has a detrimental impact on the health of small ruminants. The study's goals were the characterization of the ovine whole blood transcriptome and functional comparison of the differentially expressed genes between healthy and affected animals. The blood samples of East Frisian sheep were obtained from Cp serologically positive (3) and negative ewes (3) and the health controls (3) of another herd. Differential gene expression was analyzed by RNA-seq on an Illumina NextSeqTM 550 system using the DESeq2 approach. The DEG sets were annotated with UniProt Knowledgebase and the WEB-based GEne SeT AnaLysis Toolkit.
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
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OECD FORD obor
40203 - Husbandry
Návaznosti výsledku
Projekt
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Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2023
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů