Association of variants in antibacterial TLR genes with reproductive traits in Czech Simmental cattle

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F23%3A10005825" target="_blank" >RIV/00027014:_____/23:10005825 - isvavai.cz</a>

Výsledek na webu

<a href="https://vuzv.cz/_privat/23094.pdf" target="_blank" >https://vuzv.cz/_privat/23094.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Association of variants in antibacterial TLR genes with reproductive traits in Czech Simmental cattle

Popis výsledku v původním jazyce

Diversity in TLR genes coding for Toll-like receptors present in the Czech Simmental (Czech Red Pied) cattle population was tested for association with the female reproductive traits along with the traditionally assigned traits of infection resistance. The starting bull set of 164 animals represented complete gene pool. Hybrid resequencing with Illumina X-Ten WGS and PacBio amplicon sequencing yielded 7 and 9 SNPs in the TLR4 and TLR5 genes, respectively. The SNPs were validated with primer extension assays and characterized by the assignment to haplotypes and by function prediction. The breeding values for the reproductive traits, namely incidence of cystic ovaries, early reproductive disorders (ERD), calving ease, maternal calving ease, production longevity and calf vitality index were used for the association study.

Název v anglickém jazyce

Association of variants in antibacterial TLR genes with reproductive traits in Czech Simmental cattle

Popis výsledku anglicky

Diversity in TLR genes coding for Toll-like receptors present in the Czech Simmental (Czech Red Pied) cattle population was tested for association with the female reproductive traits along with the traditionally assigned traits of infection resistance. The starting bull set of 164 animals represented complete gene pool. Hybrid resequencing with Illumina X-Ten WGS and PacBio amplicon sequencing yielded 7 and 9 SNPs in the TLR4 and TLR5 genes, respectively. The SNPs were validated with primer extension assays and characterized by the assignment to haplotypes and by function prediction. The breeding values for the reproductive traits, namely incidence of cystic ovaries, early reproductive disorders (ERD), calving ease, maternal calving ease, production longevity and calf vitality index were used for the association study.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

40203 - Husbandry

Projekt

<a href="/cs/project/QK22020280" target="_blank" >QK22020280: Využití genomické selekce pro optimalizaci resilience dojeného skotu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů