Subpopulace lymfocytů v synoviální tekutině zdravých kloubů psů

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F04%3A00010925" target="_blank" >RIV/00027162:_____/04:00010925 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62157124:16170/04:00000237

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Lymphocyte subsets in synovial fluid from clinically healthy joints of dogs

Popis výsledku v původním jazyce

Synovial fluid samples from 19 normal (without lameness, pain, macroscopic and roentgenological changes) knees of 12 dogs were investigated for differential leukocyte counts and lymphocyte subsets using the methods of flow cytometry and anti-canine monoclonal antibodies. In all the samples, less than 5 x 106 leukocytes per millilitre were detected. Neutrophils and lymphocytes constituted less than 5% and more than 90% of all leukocytes, respectively. T-lymphocytes characterized by the expression of CD4or CD8 were found to be the predominant types in this compartment. In comparison with peripheral blood, the CD4/CD8 ratio was decreased (0.8 +/- 0.6 vs. 3.3 +/- 1.1). Majority of lymphocytes expressed the CD45RA isoform (69.4 +/- 16.7). This study is thefirst step to subsequent analyses of changes in this compartment caused by joint diseases of different aetiologies.

Název v anglickém jazyce

Lymphocyte subsets in synovial fluid from clinically healthy joints of dogs

Popis výsledku anglicky

Synovial fluid samples from 19 normal (without lameness, pain, macroscopic and roentgenological changes) knees of 12 dogs were investigated for differential leukocyte counts and lymphocyte subsets using the methods of flow cytometry and anti-canine monoclonal antibodies. In all the samples, less than 5 x 106 leukocytes per millilitre were detected. Neutrophils and lymphocytes constituted less than 5% and more than 90% of all leukocytes, respectively. T-lymphocytes characterized by the expression of CD4or CD8 were found to be the predominant types in this compartment. In comparison with peripheral blood, the CD4/CD8 ratio was decreased (0.8 +/- 0.6 vs. 3.3 +/- 1.1). Majority of lymphocytes expressed the CD45RA isoform (69.4 +/- 16.7). This study is thefirst step to subsequent analyses of changes in this compartment caused by joint diseases of different aetiologies.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2004

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Veterinaria Brno

ISSN

0001-7213

e-ISSN

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Svazek periodika

73

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

73-78

Kód UT WoS článku

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EID výsledku v databázi Scopus

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