Možné genetické poškození pracovníků českých atomových elektráren

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F06%3A%230000060" target="_blank" >RIV/00027162:_____/06:#0000060 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68378041:_____/06:00041160

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Possible genetic damage in the Czech nuclear power plant workers

Popis výsledku v původním jazyce

The aim of our study was to identify occupational risk of irradiation exposure in the Czech nuclear power plant workers. We analyzed levels of chromosomal aberrations, a well known biomarker of early biological effects and a predictor of cancer risk. Wemay conclude that low doses of ionizing radiation to which workers in the Czech nuclear power plants are exposed do not represent by themselves any significant risk of genetic damage as measured by the conventional cytogenetic analysis and FISH. Following factors were identified as potential confounders by the conventional cytogenetic analysis: XPD-6, by the FISH: age, GSTP1 and p53Bst genotypes, long-term use of medication, alcohol consumption, and smoking. No association between the dose of irradiation and the level of chromosomal aberrations in any nuclear power plant was detected either by the conventional cytogenetic analysis or by FISH.

Název v anglickém jazyce

Possible genetic damage in the Czech nuclear power plant workers

Popis výsledku anglicky

The aim of our study was to identify occupational risk of irradiation exposure in the Czech nuclear power plant workers. We analyzed levels of chromosomal aberrations, a well known biomarker of early biological effects and a predictor of cancer risk. Wemay conclude that low doses of ionizing radiation to which workers in the Czech nuclear power plants are exposed do not represent by themselves any significant risk of genetic damage as measured by the conventional cytogenetic analysis and FISH. Following factors were identified as potential confounders by the conventional cytogenetic analysis: XPD-6, by the FISH: age, GSTP1 and p53Bst genotypes, long-term use of medication, alcohol consumption, and smoking. No association between the dose of irradiation and the level of chromosomal aberrations in any nuclear power plant was detected either by the conventional cytogenetic analysis or by FISH.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

<a href="/cs/project/SL%2F5%2F160%2F05" target="_blank" >SL/5/160/05: Faktory životního prostředí ve vztahu ke zdraví</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Mutation Research

ISSN

0027-5107

e-ISSN

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Svazek periodika

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Číslo periodika v rámci svazku

1-2

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

13

Strana od-do

1-2

Kód UT WoS článku

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EID výsledku v databázi Scopus

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