Jak potvrdit identifikované toxikanty v analýze efektů

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F08%3A%230000453" target="_blank" >RIV/00027162:_____/08:#0000453 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

How to confirm identified toxicants in effect-directed analysis

Popis výsledku v původním jazyce

Effect-directed analysis (EDA) of complex environmental samples combines bioassays, fractionation and chemical analysis including confirmation of tentatively identified toxicants, spectral library information with computer-based structure generation; identified toxicants need to be confirmed as being the cause of the measured effects. Candidate components of toxic fractions may be selected based, for example, on structural alerts. Quantitative effect confirmation is based on joint effect models and prediction. Confirmation according to the Toxicity Identification Evaluation concept of the US EPA and novel tools of hazard identification help to confirm the relevance of identified compounds to populations and communities under realistic exposure conditions. Promising tools include bioavailability-directed extraction and dosing techniques, biomarker approaches and the concept of pollution-induced community tolerance.

Název v anglickém jazyce

How to confirm identified toxicants in effect-directed analysis

Popis výsledku anglicky

Effect-directed analysis (EDA) of complex environmental samples combines bioassays, fractionation and chemical analysis including confirmation of tentatively identified toxicants, spectral library information with computer-based structure generation; identified toxicants need to be confirmed as being the cause of the measured effects. Candidate components of toxic fractions may be selected based, for example, on structural alerts. Quantitative effect confirmation is based on joint effect models and prediction. Confirmation according to the Toxicity Identification Evaluation concept of the US EPA and novel tools of hazard identification help to confirm the relevance of identified compounds to populations and communities under realistic exposure conditions. Promising tools include bioavailability-directed extraction and dosing techniques, biomarker approaches and the concept of pollution-induced community tolerance.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

DN - Vliv životního prostředí na zdraví

OECD FORD obor

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Projekt

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Návaznosti

R - Projekt Ramcoveho programu EK

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Analytical and Bioanalytical Chemistry

ISSN

1618-2642

e-ISSN

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Svazek periodika

390

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

GE - Gruzie

Počet stran výsledku

15

Strana od-do

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Kód UT WoS článku

000254755700002

EID výsledku v databázi Scopus

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