The influence of age on Campylobacter jejuni infection in chicken

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F16%3AN0000020" target="_blank" >RIV/00027162:_____/16:N0000020 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0145305X16301434" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0145305X16301434</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.dci.2016.04.020" target="_blank" >10.1016/j.dci.2016.04.020</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The influence of age on Campylobacter jejuni infection in chicken

Popis výsledku v původním jazyce

Campylobacter jejuni (C. jejuni)-host-interaction may be affected by the maturation stage of the chicken's immune system and the developing gut microbipta composition. We compared these parameters between birds C jejuni-inoculated at day one, 10, 22 and 31 post hatch. The highest C jejuni-colonization rate and numbers of colony forming units (CFU) were detected in caecal content of day-one-inoculated birds while the lowest was detected in 22-days-old birds. The low bacterial colonization of 22-days-old chickens correlated with the most prominent immune reactions in this age group in comparison to other age groups. Age and C jejuni-inoculation had a significant effect on lymphocyte numbers and cytokine expression levels in caecum as well as on gut flora composition. Overall, the immune response to C. jejuni is significantly influenced by the age of the infected chickens leading to differences in C jejuni-colonization pattern between age goups. (C) 2016 Elsevier Ltd. All rights reserved.

Název v anglickém jazyce

The influence of age on Campylobacter jejuni infection in chicken

Popis výsledku anglicky

Campylobacter jejuni (C. jejuni)-host-interaction may be affected by the maturation stage of the chicken's immune system and the developing gut microbipta composition. We compared these parameters between birds C jejuni-inoculated at day one, 10, 22 and 31 post hatch. The highest C jejuni-colonization rate and numbers of colony forming units (CFU) were detected in caecal content of day-one-inoculated birds while the lowest was detected in 22-days-old birds. The low bacterial colonization of 22-days-old chickens correlated with the most prominent immune reactions in this age group in comparison to other age groups. Age and C jejuni-inoculation had a significant effect on lymphocyte numbers and cytokine expression levels in caecum as well as on gut flora composition. Overall, the immune response to C. jejuni is significantly influenced by the age of the infected chickens leading to differences in C jejuni-colonization pattern between age goups. (C) 2016 Elsevier Ltd. All rights reserved.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

<a href="/cs/project/ED0006%2F01%2F01" target="_blank" >ED0006/01/01: Centrum pro aplikovanou mikrobiologii a imunologii ve veterinární medicíne</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

ISSN

0145-305X

e-ISSN

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Svazek periodika

62

Číslo periodika v rámci svazku

SEP

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

14

Strana od-do

58-71

Kód UT WoS článku

000378456900007

EID výsledku v databázi Scopus

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