Changes in lymphocyte function and subset counts in cats with spontaneous chronic kidney disease
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F16%3AN0000092" target="_blank" >RIV/00027162:_____/16:N0000092 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/62157124:16170/16:43874269 RIV/62157124:16270/16:43874269
Výsledek na webu
<a href="http://www.agriculturejournals.cz/publicFiles/197676.pdf" target="_blank" >http://www.agriculturejournals.cz/publicFiles/197676.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.17221/282/2015-VETMED" target="_blank" >10.17221/282/2015-VETMED</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Changes in lymphocyte function and subset counts in cats with spontaneous chronic kidney disease
Popis výsledku v původním jazyce
Chronic kidney disease alters the immune response in humans and dogs and it is thought to be one of the causes of immunosuppression in cats. Haematological, biochemical, and immunological examinations were performed on blood samples obtained from 20 cats with chronic kidney disease, and were compared with the results of 18 healthy cats. In cats with chronic kidney disease, statistically significantly lower numbers of total lymphocytes (P < 0.01), especially T lymphocytes (P < 0.001), were observed. When the results were compared with the lymphocyte transformation test in healthy cats, decreased responses to phytohaemaglutinin, concanavalin A, and pokeweed mitogen were found in cats with chronic kidney disease. Our results document an alteration of counts and activity of lymphocytes in cats with chronic kidney disease. Thus, higher usceptibility to infection may be expected in these patients.
Název v anglickém jazyce
Changes in lymphocyte function and subset counts in cats with spontaneous chronic kidney disease
Popis výsledku anglicky
Chronic kidney disease alters the immune response in humans and dogs and it is thought to be one of the causes of immunosuppression in cats. Haematological, biochemical, and immunological examinations were performed on blood samples obtained from 20 cats with chronic kidney disease, and were compared with the results of 18 healthy cats. In cats with chronic kidney disease, statistically significantly lower numbers of total lymphocytes (P < 0.01), especially T lymphocytes (P < 0.001), were observed. When the results were compared with the lymphocyte transformation test in healthy cats, decreased responses to phytohaemaglutinin, concanavalin A, and pokeweed mitogen were found in cats with chronic kidney disease. Our results document an alteration of counts and activity of lymphocytes in cats with chronic kidney disease. Thus, higher usceptibility to infection may be expected in these patients.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
GJ - Choroby a škůdci zvířat, veterinární medicina
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/LO1218" target="_blank" >LO1218: Zdravé zvíře jako zdroj zdravé potraviny</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2016
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Veterinární medicína
ISSN
0375-8427
e-ISSN
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Svazek periodika
61
Číslo periodika v rámci svazku
10
Stát vydavatele periodika
CZ - Česká republika
Počet stran výsledku
7
Strana od-do
553-559
Kód UT WoS článku
000386020600003
EID výsledku v databázi Scopus
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