Residues of drugs used to treat diseases of affluence and their effects on zebrafish embryos (Danio rerio)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F22%3AN0000052" target="_blank" >RIV/00027162:_____/22:N0000052 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00027162:_____/23:N0000042

Výsledek na webu

<a href="https://www.vfu.cz/files/upload/733/Program%20XXIV.%20KMVP%202022.pdf" target="_blank" >https://www.vfu.cz/files/upload/733/Program%20XXIV.%20KMVP%202022.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Residues of drugs used to treat diseases of affluence and their effects on zebrafish embryos (Danio rerio)

Popis výsledku v původním jazyce

Contamination of the aquatic environment with residues of drugs used for the treatment of diseases of affluence is constantly increasing. One of the reasons is imperfect purification in wastewater treatment plants. Another reason is the increasing prescribes and uses of these drugs. Drug residues can have a negative effect on aquatic environment and non-target aquatic organisms. In our study, the toxicity of metformin, metoprolol and enalapril on zebrafish (Danio rerio) embryos in five different concentrations was tested. The acute toxicity test was performed according to OECD Guideline No 236. As a result, various negative effect on embryos exposed to metformin, metoprolol and enalapril were observed.

Název v anglickém jazyce

Residues of drugs used to treat diseases of affluence and their effects on zebrafish embryos (Danio rerio)

Popis výsledku anglicky

Contamination of the aquatic environment with residues of drugs used for the treatment of diseases of affluence is constantly increasing. One of the reasons is imperfect purification in wastewater treatment plants. Another reason is the increasing prescribes and uses of these drugs. Drug residues can have a negative effect on aquatic environment and non-target aquatic organisms. In our study, the toxicity of metformin, metoprolol and enalapril on zebrafish (Danio rerio) embryos in five different concentrations was tested. The acute toxicity test was performed according to OECD Guideline No 236. As a result, various negative effect on embryos exposed to metformin, metoprolol and enalapril were observed.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

40301 - Veterinary science

Projekt

<a href="/cs/project/EF16_019%2F0000869" target="_blank" >EF16_019/0000869: Udržitelná produkce zdravých ryb v různých akvakulturních systémech - PROFISH</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů