The effect of oral microplastics and flame retardants application on the selected genes expression of rainbow trout (Oncorhynchus mykiss)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F22%3AN0000099" target="_blank" >RIV/00027162:_____/22:N0000099 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The effect of oral microplastics and flame retardants application on the selected genes expression of rainbow trout (Oncorhynchus mykiss)

Popis výsledku v původním jazyce

Plastic pollution is a global problem caused by an excessive use of this material, high resistance in environment and poor waste management. One of the most common type of plastic polluting the environment is polystyrene (PS), which commonly contains flame-retardant, hexabromocyclododecane (HBCD), in high percentage. In general, oral ingestion of MPs can cause mechanical damage and obstruction of digestive tract and particles ˂ 600 μm are able to cross intestinal barriers, enter the blood stream and can be transported to tissues. While in vertebrates, the toxicity of HBCD has been extensively studied with discovered reproductive and developmental toxicity, neurotoxicity, mutagenicity, as well as endocrine disrupting effects, the mechanism of toxicity is not fully clarified in fish to date. This study was focused on the analysis of genes via gene expression, which will be the basis for further analyses.

Název v anglickém jazyce

The effect of oral microplastics and flame retardants application on the selected genes expression of rainbow trout (Oncorhynchus mykiss)

Popis výsledku anglicky

Plastic pollution is a global problem caused by an excessive use of this material, high resistance in environment and poor waste management. One of the most common type of plastic polluting the environment is polystyrene (PS), which commonly contains flame-retardant, hexabromocyclododecane (HBCD), in high percentage. In general, oral ingestion of MPs can cause mechanical damage and obstruction of digestive tract and particles ˂ 600 μm are able to cross intestinal barriers, enter the blood stream and can be transported to tissues. While in vertebrates, the toxicity of HBCD has been extensively studied with discovered reproductive and developmental toxicity, neurotoxicity, mutagenicity, as well as endocrine disrupting effects, the mechanism of toxicity is not fully clarified in fish to date. This study was focused on the analysis of genes via gene expression, which will be the basis for further analyses.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

40301 - Veterinary science

Projekt

<a href="/cs/project/EF16_019%2F0000869" target="_blank" >EF16_019/0000869: Udržitelná produkce zdravých ryb v různých akvakulturních systémech - PROFISH</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů