Long-term pedigree analysis: An effective tool for managing congenital malformations in cattle
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F22%3AN0000126" target="_blank" >RIV/00027162:_____/22:N0000126 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/60460709:41210/22:91793
Výsledek na webu
<a href="https://www.agriculturejournals.cz/web/cjas.htm?type=article&id=70_2022-CJAS" target="_blank" >https://www.agriculturejournals.cz/web/cjas.htm?type=article&id=70_2022-CJAS</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.17221/70/2022-CJAS" target="_blank" >10.17221/70/2022-CJAS</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Long-term pedigree analysis: An effective tool for managing congenital malformations in cattle
Popis výsledku v původním jazyce
The study aims to analyze pedigrees of calves affected by three congenital defects, Aplasia genitalis, Atresia ani et recti and Hernia cerebralis. The defects were diagnosed by veterinary surgeons to the Czech surveillance program for bovine genetic disorders. The sires fathering affected calves were born in the Czech Republic or imported 1986-2001. The cases occurred on farms across the Czech Republic. The pedigree of each case was examined for common maternal and paternal ancestors (inbreeding loops) and for ancestors shared by other cases. The 13 calves affected by Aplasia genitalis have in all cases common ancestors. The results indicate hereditary causation with recessive inheritance. Also in Atresia ani et recti some pedigrees of 25 affected calves support the hereditary causation, repeating ancestors were found for 11 calves. Contrarily, our analysis of 11 Hernia cerebralis cases did not approved the genetic background. The pedigree analysis of congenital defects could help in controlling of genetic health, but the final goal is the description of causal genes and mutations. The measures against sires fathering affected calves should be appropriate to the state of current knowledge, in some cases culling, on other occasions prudent use in breeding with monitoring of descendants.
Název v anglickém jazyce
Long-term pedigree analysis: An effective tool for managing congenital malformations in cattle
Popis výsledku anglicky
The study aims to analyze pedigrees of calves affected by three congenital defects, Aplasia genitalis, Atresia ani et recti and Hernia cerebralis. The defects were diagnosed by veterinary surgeons to the Czech surveillance program for bovine genetic disorders. The sires fathering affected calves were born in the Czech Republic or imported 1986-2001. The cases occurred on farms across the Czech Republic. The pedigree of each case was examined for common maternal and paternal ancestors (inbreeding loops) and for ancestors shared by other cases. The 13 calves affected by Aplasia genitalis have in all cases common ancestors. The results indicate hereditary causation with recessive inheritance. Also in Atresia ani et recti some pedigrees of 25 affected calves support the hereditary causation, repeating ancestors were found for 11 calves. Contrarily, our analysis of 11 Hernia cerebralis cases did not approved the genetic background. The pedigree analysis of congenital defects could help in controlling of genetic health, but the final goal is the description of causal genes and mutations. The measures against sires fathering affected calves should be appropriate to the state of current knowledge, in some cases culling, on other occasions prudent use in breeding with monitoring of descendants.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
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OECD FORD obor
40301 - Veterinary science
Návaznosti výsledku
Projekt
<a href="/cs/project/QK1910320" target="_blank" >QK1910320: Výzkum postupů šlechtění dojeného skotu s cílem zvýšit odolnost k nemocem využitím genomických plemenných hodnot, rozvoje systému sběru zdravotních dat a cílené genotypizace skotu</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2022
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Czech Journal of Animal Science
ISSN
1212-1819
e-ISSN
1805-9309
Svazek periodika
67
Číslo periodika v rámci svazku
10
Stát vydavatele periodika
CZ - Česká republika
Počet stran výsledku
9
Strana od-do
385-393
Kód UT WoS článku
000879515500001
EID výsledku v databázi Scopus
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