Diversity of Streptococcus suis strains isolated from sick pigs from farms in the Czech Republic

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F22%3AN0000137" target="_blank" >RIV/00027162:_____/22:N0000137 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00027162:_____/23:N0000060

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Diversity of Streptococcus suis strains isolated from sick pigs from farms in the Czech Republic

Popis výsledku v původním jazyce

Streptococcus suis is a significant cause of mortality in piglets and growing pigs worldwide. The pathogenic strains causes meningitis, arthritis, endocarditis, polyserositis, and septicemia and are also considered an emerging zoonotic pathogen. Serotyping and multilocus sequence typing are primary methods to differentiate strains. The objective of this study was to characterize the diversity of 552 S. suis isolates collected between 2018 and 2022 originating from sick pigs from farms in the Czech Republic. Using molecular methods, serotype 7 (15.2%) was determined to be predominant among S. suis isolates, followed by serotypes 2, 1/2, 9, 8, 4, 3, 1, 29, 31, 16, 12, and 15. Other serotypes were identified either rarely (up to 10 cases) or not at all, 18.5% of isolates were non-typeable. Multilocus sequence typing revealed 56 sequence types, of which 29 was identified as novel. The predominant sequence types were ST29 and ST28. No direct relationship between serotypes and sequence types was detected. Eleven of the 23 serotypes identified contained multiple sequence types, with the number of different sequence types within a single serotype ranging from 2 to 6. The distribution of serotypes and sequence types showed the large diversity of the S. suis strains in pig farms. This work was supported by Ministry of Agriculture of the Czech Republic (Institutional Support No.MZE-RO0518) and by the National Agency for Agricultural Research (Project No. QK1810193).

Název v anglickém jazyce

Diversity of Streptococcus suis strains isolated from sick pigs from farms in the Czech Republic

Popis výsledku anglicky

Streptococcus suis is a significant cause of mortality in piglets and growing pigs worldwide. The pathogenic strains causes meningitis, arthritis, endocarditis, polyserositis, and septicemia and are also considered an emerging zoonotic pathogen. Serotyping and multilocus sequence typing are primary methods to differentiate strains. The objective of this study was to characterize the diversity of 552 S. suis isolates collected between 2018 and 2022 originating from sick pigs from farms in the Czech Republic. Using molecular methods, serotype 7 (15.2%) was determined to be predominant among S. suis isolates, followed by serotypes 2, 1/2, 9, 8, 4, 3, 1, 29, 31, 16, 12, and 15. Other serotypes were identified either rarely (up to 10 cases) or not at all, 18.5% of isolates were non-typeable. Multilocus sequence typing revealed 56 sequence types, of which 29 was identified as novel. The predominant sequence types were ST29 and ST28. No direct relationship between serotypes and sequence types was detected. Eleven of the 23 serotypes identified contained multiple sequence types, with the number of different sequence types within a single serotype ranging from 2 to 6. The distribution of serotypes and sequence types showed the large diversity of the S. suis strains in pig farms. This work was supported by Ministry of Agriculture of the Czech Republic (Institutional Support No.MZE-RO0518) and by the National Agency for Agricultural Research (Project No. QK1810193).

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

40301 - Veterinary science

Projekt

<a href="/cs/project/QK1810193" target="_blank" >QK1810193: Moderní metody diagnostiky, terapie a prevence infekcí Streptococcus suis jako nástroj pro sestavování cílených kontrolních programů v chovech prasat</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů