Feeding-Regime-Dependent Intestinal Response of Rainbow Trout after Administration of a Novel Probiotic Feed

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F23%3AN0000068" target="_blank" >RIV/00027162:_____/23:N0000068 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62156489:43210/23:43923770

Výsledek na webu

<a href="https://www.mdpi.com/2076-2615/13/12/1892" target="_blank" >https://www.mdpi.com/2076-2615/13/12/1892</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/ani13121892" target="_blank" >10.3390/ani13121892</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Feeding-Regime-Dependent Intestinal Response of Rainbow Trout after Administration of a Novel Probiotic Feed

Popis výsledku v původním jazyce

In this study, we tested the autochthonous trout probiotic strain L. plantarum R2 BiocenolTM in a newly developed low-cost application form ensuring rapid revitalization of bacteria. We tested the continuous and cyclic feeding regime with regard to its effect on the intestinal immune response and microbiota of rainbow trout. We found that during the continuous application of probiotic feed, the immune system adapts to the immunomodulator and there is no substantial stimulation of the intestinal immune response. On the other hand, after a 3-week break in probiotic feeding and reintroduction of probiotics, there was a significant stimulation of gene expression of molecules associated with both cellular and humoral immunity (CD8, IgM, TGF-β, IL8, TLR9), but without a significant increase in the basic pro-inflammatory cytokines IL1 and TNF-α. We can conclude that in aquaculture it can be used as a continuous application, which does not cause excessive immunostimulation, as well as a cyclic application, which provides the opportunity to stimulate the immunity of trout, for example, in periods of stress. The newly developed application form proved to be suitable, as the fish accepted it without any problems.

Název v anglickém jazyce

Feeding-Regime-Dependent Intestinal Response of Rainbow Trout after Administration of a Novel Probiotic Feed

Popis výsledku anglicky

In this study, we tested the autochthonous trout probiotic strain L. plantarum R2 BiocenolTM in a newly developed low-cost application form ensuring rapid revitalization of bacteria. We tested the continuous and cyclic feeding regime with regard to its effect on the intestinal immune response and microbiota of rainbow trout. We found that during the continuous application of probiotic feed, the immune system adapts to the immunomodulator and there is no substantial stimulation of the intestinal immune response. On the other hand, after a 3-week break in probiotic feeding and reintroduction of probiotics, there was a significant stimulation of gene expression of molecules associated with both cellular and humoral immunity (CD8, IgM, TGF-β, IL8, TLR9), but without a significant increase in the basic pro-inflammatory cytokines IL1 and TNF-α. We can conclude that in aquaculture it can be used as a continuous application, which does not cause excessive immunostimulation, as well as a cyclic application, which provides the opportunity to stimulate the immunity of trout, for example, in periods of stress. The newly developed application form proved to be suitable, as the fish accepted it without any problems.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40103 - Fishery

Projekt

<a href="/cs/project/EF16_019%2F0000869" target="_blank" >EF16_019/0000869: Udržitelná produkce zdravých ryb v různých akvakulturních systémech - PROFISH</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Animals

ISSN

2076-2615

e-ISSN

2076-2615

Svazek periodika

13

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

24

Strana od-do

—

Kód UT WoS článku

001016893700001

EID výsledku v databázi Scopus

2-s2.0-85163830695