Chickens as a model for host-gut microbiota studies

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F25%3AN0000124" target="_blank" >RIV/00027162:_____/25:N0000124 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Chickens as a model for host-gut microbiota studies

Popis výsledku v původním jazyce

15th Host Pathogen Interaction Forum 2025, 10-13 October 2025. Třešť, Česká republika. Around 240 million chickens are hatched annually in the Czech Republic what corresponds to approx. 1 million chickens produced every working day. This makes this animal simply available and high production also reduces cost of a single chick. Moreover, since chicks are hatched in hatcheries without any contact with parents, millions of chicks are available every week and these might be colonised with microbiota of various composition. Although ignoring some facts which are influenced by raising of chicks in the absence of adult birds may lead to confounding conclusions on development of chicken gut microbiota, once correctly understood, there is no longer better animal model than chicken. Newly hatched chicks can be oral inoculated with faecal material from adult hens and microbiota increasing chicken resistance can be selected. If the selection is modified towards body weight increase, microbiota positively affecting growth can be identified. Following administration of faecal material, microbiota colonising gut lumen and gut mucosal surfaces can be defined. It is also possible to have an access to chicks 1, 2, 3 or 4 days of age and define fine development of gut microbiota before and after beginning of feed income. Finally, not only bacteria but also phages specific against particular bacterial species can be easily tested in chickens.

Název v anglickém jazyce

Chickens as a model for host-gut microbiota studies

Popis výsledku anglicky

15th Host Pathogen Interaction Forum 2025, 10-13 October 2025. Třešť, Česká republika. Around 240 million chickens are hatched annually in the Czech Republic what corresponds to approx. 1 million chickens produced every working day. This makes this animal simply available and high production also reduces cost of a single chick. Moreover, since chicks are hatched in hatcheries without any contact with parents, millions of chicks are available every week and these might be colonised with microbiota of various composition. Although ignoring some facts which are influenced by raising of chicks in the absence of adult birds may lead to confounding conclusions on development of chicken gut microbiota, once correctly understood, there is no longer better animal model than chicken. Newly hatched chicks can be oral inoculated with faecal material from adult hens and microbiota increasing chicken resistance can be selected. If the selection is modified towards body weight increase, microbiota positively affecting growth can be identified. Following administration of faecal material, microbiota colonising gut lumen and gut mucosal surfaces can be defined. It is also possible to have an access to chicks 1, 2, 3 or 4 days of age and define fine development of gut microbiota before and after beginning of feed income. Finally, not only bacteria but also phages specific against particular bacterial species can be easily tested in chickens.

Druh

O - Ostatní výsledky

CEP obor

—

OECD FORD obor

40301 - Veterinary science

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů