Ionized Magnesium and Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F16%3A10325258" target="_blank" >RIV/00064165:_____/16:10325258 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/16:10325258

Výsledek na webu

<a href="http://www.karger.com/Article/Pdf/440972" target="_blank" >http://www.karger.com/Article/Pdf/440972</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000440972" target="_blank" >10.1159/000440972</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Ionized Magnesium and Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy

Popis výsledku v původním jazyce

Background: The regional citrate anticoagulation (RCA) induces changes in total (Ca-tot) and ionized (Ca2+) calcium. As of now, we do not have much information about parallel changes of total (Mg-tot) and ionized (Mg2+) magnesium. Methods: The authors compared changes of Mg2+ and Mg-tot with changes of Ca2+ and Ca-tot in 32 critically ill patients on 4% trisodium citrate (4% TSC) with calcium-free fluids. Results: The median continuous venovenous hemodiafiltration balance of Mg-tot was -0.91 (-1.18 to -0.53) mmol/h compared to the median balance of Ca-tot 0.86 (0.08-1.55) mmol/h. Postfilter Mg2+ decreased by 68.3% (70.8-65.6) in parallel (r = 0.41, p = 0.03) to decrease of postfilter Ca2+ (by 70.2% (73.0-66.1)) and was significantly related to the postfilter Ca2+ (r = 0.50, p < 0.001). The decrease of prefilter to postfilter Ca2+ correlated to a dosage of 4% TSC per blood flow (r = 0.37, p = 0.04). Conclusions: The loss of Mg-tot during RCA is not covered by magnesium concentration in ordinary dialysis/substitution fluid and may lead to the depletion of total body magnesium. The postfilter Mg2+ is significantly related to the postfilter Ca2+. Video Journal Club "Cappuccino with Claudio Ronco" at http://www.karger.com/?doi = 440972.

Název v anglickém jazyce

Ionized Magnesium and Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy

Popis výsledku anglicky

Background: The regional citrate anticoagulation (RCA) induces changes in total (Ca-tot) and ionized (Ca2+) calcium. As of now, we do not have much information about parallel changes of total (Mg-tot) and ionized (Mg2+) magnesium. Methods: The authors compared changes of Mg2+ and Mg-tot with changes of Ca2+ and Ca-tot in 32 critically ill patients on 4% trisodium citrate (4% TSC) with calcium-free fluids. Results: The median continuous venovenous hemodiafiltration balance of Mg-tot was -0.91 (-1.18 to -0.53) mmol/h compared to the median balance of Ca-tot 0.86 (0.08-1.55) mmol/h. Postfilter Mg2+ decreased by 68.3% (70.8-65.6) in parallel (r = 0.41, p = 0.03) to decrease of postfilter Ca2+ (by 70.2% (73.0-66.1)) and was significantly related to the postfilter Ca2+ (r = 0.50, p < 0.001). The decrease of prefilter to postfilter Ca2+ correlated to a dosage of 4% TSC per blood flow (r = 0.37, p = 0.04). Conclusions: The loss of Mg-tot during RCA is not covered by magnesium concentration in ordinary dialysis/substitution fluid and may lead to the depletion of total body magnesium. The postfilter Mg2+ is significantly related to the postfilter Ca2+. Video Journal Club "Cappuccino with Claudio Ronco" at http://www.karger.com/?doi = 440972.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

—

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Blood Purification

ISSN

0253-5068

e-ISSN

—

Svazek periodika

41

Číslo periodika v rámci svazku

1-3

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

7

Strana od-do

41-47

Kód UT WoS článku

000371790200007

EID výsledku v databázi Scopus

2-s2.0-84945136305