Premature infants born at <25 weeks of gestation may be compromised by currently recommended resuscitation techniques

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F16%3A10325269" target="_blank" >RIV/00064165:_____/16:10325269 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/16:10325269

Výsledek na webu

<a href="http://onlinelibrary.wiley.com/doi/10.1111/apa.13178/epdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/apa.13178/epdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/apa.13178" target="_blank" >10.1111/apa.13178</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Premature infants born at <25 weeks of gestation may be compromised by currently recommended resuscitation techniques

Popis výsledku v původním jazyce

AimStandard resuscitation guidelines are based on data from a range of gestational ages. We sought to evaluate the effectiveness of our delivery room resuscitation protocol across a range of gestational ages in preterm infants born at <29weeks. MethodsWe performed an observational study of prospectively collected video recordings of 73 preterm infants. The percentage of bradycardic patients, time to reach target oxygen saturation and the extent of all interventions were compared between three gestational age groups: 22-24weeks (n=22), 25-26weeks (n=27) and 27-28weeks (n=24). ResultsAlthough the same resuscitation protocol was followed for all infants, bradycardic infants born <25weeks responded poorly and required significantly longer to reach oxygen saturation targets of >70%, >80% and >90% (p<0.03). They required significantly more interventions and had higher rate of death (p<0.05) and severe intraventricular haemorrhage (p<0.03). Significantly lower heart rate and oxygen saturation values were found in infants with intraventricular haemorrhage. ConclusionCurrent recommendations for resuscitation may fail to achieve timely lung aeration in infants born at the borderline of viability, leading to higher mortality and morbidity. Sustained inflation and delayed cord clamping may be effective alternatives.

Název v anglickém jazyce

Premature infants born at <25 weeks of gestation may be compromised by currently recommended resuscitation techniques

Popis výsledku anglicky

AimStandard resuscitation guidelines are based on data from a range of gestational ages. We sought to evaluate the effectiveness of our delivery room resuscitation protocol across a range of gestational ages in preterm infants born at <29weeks. MethodsWe performed an observational study of prospectively collected video recordings of 73 preterm infants. The percentage of bradycardic patients, time to reach target oxygen saturation and the extent of all interventions were compared between three gestational age groups: 22-24weeks (n=22), 25-26weeks (n=27) and 27-28weeks (n=24). ResultsAlthough the same resuscitation protocol was followed for all infants, bradycardic infants born <25weeks responded poorly and required significantly longer to reach oxygen saturation targets of >70%, >80% and >90% (p<0.03). They required significantly more interventions and had higher rate of death (p<0.05) and severe intraventricular haemorrhage (p<0.03). Significantly lower heart rate and oxygen saturation values were found in infants with intraventricular haemorrhage. ConclusionCurrent recommendations for resuscitation may fail to achieve timely lung aeration in infants born at the borderline of viability, leading to higher mortality and morbidity. Sustained inflation and delayed cord clamping may be effective alternatives.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FK - Gynekologie a porodnictví

OECD FORD obor

—

Projekt

—

Návaznosti

O - Projekt operacniho programu

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Paediatrica

ISSN

0803-5253

e-ISSN

—

Svazek periodika

105

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

"E142"-"E150"

Kód UT WoS článku

000371892200001

EID výsledku v databázi Scopus

2-s2.0-84949267433