Glucose variability, HbA1c and microvascular complications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F16%3A10325531" target="_blank" >RIV/00064165:_____/16:10325531 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/16:10325531

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s11154-016-9347-2" target="_blank" >http://dx.doi.org/10.1007/s11154-016-9347-2</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11154-016-9347-2" target="_blank" >10.1007/s11154-016-9347-2</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Glucose variability, HbA1c and microvascular complications

Popis výsledku v původním jazyce

Microvascular complications in diabetes are associated with poor long-term diabetes control as measured by HbA1c levels. Glucose fluctuations are related to oxidative stress, endothelial dysfunction, and inflammation, factors traditionally associated with the pathogenesis of vascular damage. Glucose variability has been associated with macrovascular disease in some studies but any association with microvascular disease remains controversial. This overview summarizes recent findings in the field of glucose variability and its possible relationship with retinopathy, nephropathy and neuropathy. It is concluded that randomized prospective follow-up trials could possibly help estimate whether short-term glucose variability should be considered as an independent risk factor for microvascular complications in diabetes.

Název v anglickém jazyce

Glucose variability, HbA1c and microvascular complications

Popis výsledku anglicky

Microvascular complications in diabetes are associated with poor long-term diabetes control as measured by HbA1c levels. Glucose fluctuations are related to oxidative stress, endothelial dysfunction, and inflammation, factors traditionally associated with the pathogenesis of vascular damage. Glucose variability has been associated with macrovascular disease in some studies but any association with microvascular disease remains controversial. This overview summarizes recent findings in the field of glucose variability and its possible relationship with retinopathy, nephropathy and neuropathy. It is concluded that randomized prospective follow-up trials could possibly help estimate whether short-term glucose variability should be considered as an independent risk factor for microvascular complications in diabetes.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

—

Projekt

<a href="/cs/project/NV15-26705A" target="_blank" >NV15-26705A: Vliv glukózové variability na patogenetické mechanizmy rozvoje cévních změn při diabetu 1. typu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Reviews in Endocrine and Metabolic Disorders

ISSN

1389-9155

e-ISSN

—

Svazek periodika

17

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

103-110

Kód UT WoS článku

000376887800011

EID výsledku v databázi Scopus

2-s2.0-84961140572