Impulse control disorders in patients with young-onset Parkinson's disease: A cross-sectional study seeking associated factors

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F16%3A10330363" target="_blank" >RIV/00064165:_____/16:10330363 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/16:10330363 RIV/00159816:_____/16:00066880 RIV/00216224:14110/16:00088955

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.baga.2016.09.001" target="_blank" >http://dx.doi.org/10.1016/j.baga.2016.09.001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.baga.2016.09.001" target="_blank" >10.1016/j.baga.2016.09.001</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Impulse control disorders in patients with young-onset Parkinson's disease: A cross-sectional study seeking associated factors

Popis výsledku v původním jazyce

Introduction: The aim of this cross-sectional study was to investigate the frequency and factors associated with impulse control disorder (ICD) symptoms, including personality characteristics, in Czech young-onset Parkinson's disease (PD) patients. Subjects and methods: We examined 49 young-onset PD patients and 38 age-matched control subjects. ICD symptoms were identified using the South Oaks Gambling Screen and modified Minnesota Impulse Disorders Interview. Results: A higher prevalence of pathological gambling and hypersexuality was found in PD patients than in control subjects. A higher frequency of pathological gambling in our sample of young-onset PD patients was found in patients using dopamine agonists and in patients with dyskinesias lasting 5 or more years. The frequency of any ICD symptom was associated with coffee consumption, higher reported anxiety, and somatization. ICD symptoms were also related to personality characteristics in PD patients; specifically, patients who manifested any ICD symptom scored significantly higher on Self-assertive/ Antisocial and Reserved/Schizoid personality styles and pathological gambling was associated with lower reported Conscientiousness. Conclusion: Our results demonstrate that ICD presents a real problem in young-onset PD patients. Knowledge about the factors associated with ICD symptoms might be helpful in the proactive search for these pathological behaviours in this specific subgroup of PD patients.

Název v anglickém jazyce

Impulse control disorders in patients with young-onset Parkinson's disease: A cross-sectional study seeking associated factors

Popis výsledku anglicky

Introduction: The aim of this cross-sectional study was to investigate the frequency and factors associated with impulse control disorder (ICD) symptoms, including personality characteristics, in Czech young-onset Parkinson's disease (PD) patients. Subjects and methods: We examined 49 young-onset PD patients and 38 age-matched control subjects. ICD symptoms were identified using the South Oaks Gambling Screen and modified Minnesota Impulse Disorders Interview. Results: A higher prevalence of pathological gambling and hypersexuality was found in PD patients than in control subjects. A higher frequency of pathological gambling in our sample of young-onset PD patients was found in patients using dopamine agonists and in patients with dyskinesias lasting 5 or more years. The frequency of any ICD symptom was associated with coffee consumption, higher reported anxiety, and somatization. ICD symptoms were also related to personality characteristics in PD patients; specifically, patients who manifested any ICD symptom scored significantly higher on Self-assertive/ Antisocial and Reserved/Schizoid personality styles and pathological gambling was associated with lower reported Conscientiousness. Conclusion: Our results demonstrate that ICD presents a real problem in young-onset PD patients. Knowledge about the factors associated with ICD symptoms might be helpful in the proactive search for these pathological behaviours in this specific subgroup of PD patients.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

—

Projekt

<a href="/cs/project/NV15-30062A" target="_blank" >NV15-30062A: Fenotypy impulzivity u neuropsychiatrických poruch a jejich klinický význam</a><br>

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Basal Ganglia

ISSN

2210-5336

e-ISSN

—

Svazek periodika

6

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

IT - Italská republika

Počet stran výsledku

9

Strana od-do

197-205

Kód UT WoS článku

000389532600004

EID výsledku v databázi Scopus

2-s2.0-84992035746