Narcolepsy with cataplexy in patients aged over 60 years: a case-control study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F16%3A10331402" target="_blank" >RIV/00064165:_____/16:10331402 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/16:10331402 RIV/00216208:11210/16:10331402

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.sleep.2016.05.011" target="_blank" >http://dx.doi.org/10.1016/j.sleep.2016.05.011</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.sleep.2016.05.011" target="_blank" >10.1016/j.sleep.2016.05.011</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Narcolepsy with cataplexy in patients aged over 60 years: a case-control study

Popis výsledku v původním jazyce

Objective: Narcolepsy with cataplexy (NC) is a chronic disabling disease; however, there are insufficient data on older NC subjects. Methods: A cross-sectional evaluation on health and social status, including intensity and progression of NC symptoms, was performed on 42 NC patients (age 71.9 years +/- 7.5) and 46 age-and-sex-matched controls (age 72.2 years +/- 7.0). Results: A greater proportion of patients than controls suffered from hypertension and type 2 diabetes. More controls had a history of treated depression; however, according to the Geriatric Depression Scale, more NC patients scored in the range of depression. There were no significant differences in Addenbrook Cognitive Examination scores. Average physical fitness assessed by the Short Physical Performance Battery was lower in the NC group. The frequency of meeting with family, friends, and participation in hobbies or sports did not differ between the two groups. Conclusions: Symptoms of NC were present throughout life. Comorbidities and lower physical fitness, which are known to be present in young and middle-aged NC subjects, were also present in older patients. Although NC subjects were less professionally active during their lifetime, they did not differ from controls in important social parameters in older age.

Název v anglickém jazyce

Narcolepsy with cataplexy in patients aged over 60 years: a case-control study

Popis výsledku anglicky

Objective: Narcolepsy with cataplexy (NC) is a chronic disabling disease; however, there are insufficient data on older NC subjects. Methods: A cross-sectional evaluation on health and social status, including intensity and progression of NC symptoms, was performed on 42 NC patients (age 71.9 years +/- 7.5) and 46 age-and-sex-matched controls (age 72.2 years +/- 7.0). Results: A greater proportion of patients than controls suffered from hypertension and type 2 diabetes. More controls had a history of treated depression; however, according to the Geriatric Depression Scale, more NC patients scored in the range of depression. There were no significant differences in Addenbrook Cognitive Examination scores. Average physical fitness assessed by the Short Physical Performance Battery was lower in the NC group. The frequency of meeting with family, friends, and participation in hobbies or sports did not differ between the two groups. Conclusions: Symptoms of NC were present throughout life. Comorbidities and lower physical fitness, which are known to be present in young and middle-aged NC subjects, were also present in older patients. Although NC subjects were less professionally active during their lifetime, they did not differ from controls in important social parameters in older age.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

—

Projekt

<a href="/cs/project/NT13238" target="_blank" >NT13238: Narkolepsie – klinika, patofyziologie, stárnutí, komorbidity a pohybový režim.</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Sleep Medicine

ISSN

1389-9457

e-ISSN

—

Svazek periodika

26

Číslo periodika v rámci svazku

October

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

79-84

Kód UT WoS článku

000390720900016

EID výsledku v databázi Scopus

2-s2.0-84994544550