Gender differences and survival after out of hospital cardiac arrest

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F22%3A10445740" target="_blank" >RIV/00064165:_____/22:10445740 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/22:10445740 RIV/00216208:11320/22:10445740

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=zhZrjvaE.E" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=zhZrjvaE.E</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ajem.2022.02.032" target="_blank" >10.1016/j.ajem.2022.02.032</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Gender differences and survival after out of hospital cardiac arrest

Popis výsledku v původním jazyce

Background: Published evidence regarding the effect of gender on outcome after out of hospital cardiac arrest (OHCA) is inconsistent. We aimed to investigate the association of gender to outcome and resuscitation characteristics in OHCA patients admitted to the cardiac arrest center. Methods: In this retrospective analysis of prospective registry data, all patients admitted for OHCA were included. The influence of gender on 30-day survival and good neurological outcome (cerebral performance category of 1 or 2) were examined using Kaplan-Meier estimates and multivariable logistic regression. Results: In total, 932 patients were analysed (239 women, 26%). Women were older (64 vs 60 years, p&lt;0.001) and less commonly had a shockable rhythm(47% vs 65%, P&lt;0.001) compared to men. Women were less likely to have a cardiac cause of arrest (54% vs. 75%, p&lt;0.001), received less therapeutic hypothermia (74% vs 86%, p&lt;0.001) and coronary angiography (63% vs. 79%, p&lt;0.001). The overall 30-day survival was lower for women (45% vs. 53%, log-rank p = 0.005) as well as good neurological outcome (37% vs. 46%, p = 0.008). However, according to the multivariate logistic regression, gender was not associated with survival (OR 0.98, 95% CI 0.65-1.50, p = 0.94) nor with good neurological outcome (OR 0.91, 95% CI 0.59-1.40, p = 0.67). Conclusion: Women admitted for OHCA to a cardiac center had a different cause of arrest that had a different treatment and outcome compared to men. Survival and good neurological outcome were lower in women, however, after adjusting for baseline characteristics, gender was not associated with survival nor neurological outcome. (C) 2022 Elsevier Inc. All rights reserved.

Název v anglickém jazyce

Gender differences and survival after out of hospital cardiac arrest

Popis výsledku anglicky

Background: Published evidence regarding the effect of gender on outcome after out of hospital cardiac arrest (OHCA) is inconsistent. We aimed to investigate the association of gender to outcome and resuscitation characteristics in OHCA patients admitted to the cardiac arrest center. Methods: In this retrospective analysis of prospective registry data, all patients admitted for OHCA were included. The influence of gender on 30-day survival and good neurological outcome (cerebral performance category of 1 or 2) were examined using Kaplan-Meier estimates and multivariable logistic regression. Results: In total, 932 patients were analysed (239 women, 26%). Women were older (64 vs 60 years, p&lt;0.001) and less commonly had a shockable rhythm(47% vs 65%, P&lt;0.001) compared to men. Women were less likely to have a cardiac cause of arrest (54% vs. 75%, p&lt;0.001), received less therapeutic hypothermia (74% vs 86%, p&lt;0.001) and coronary angiography (63% vs. 79%, p&lt;0.001). The overall 30-day survival was lower for women (45% vs. 53%, log-rank p = 0.005) as well as good neurological outcome (37% vs. 46%, p = 0.008). However, according to the multivariate logistic regression, gender was not associated with survival (OR 0.98, 95% CI 0.65-1.50, p = 0.94) nor with good neurological outcome (OR 0.91, 95% CI 0.59-1.40, p = 0.67). Conclusion: Women admitted for OHCA to a cardiac center had a different cause of arrest that had a different treatment and outcome compared to men. Survival and good neurological outcome were lower in women, however, after adjusting for baseline characteristics, gender was not associated with survival nor neurological outcome. (C) 2022 Elsevier Inc. All rights reserved.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

The American Journal of Emergency Medicine

ISSN

0735-6757

e-ISSN

1532-8171

Svazek periodika

55

Číslo periodika v rámci svazku

May

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

27-31

Kód UT WoS článku

000830080600005

EID výsledku v databázi Scopus

2-s2.0-85126826886