Semi-automatic quantification of mosaic perfusion of lung parenchyma and its correlation with haemodynamic parameters in patients with chronic thromboembolic pulmonary hypertension

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F23%3A10472577" target="_blank" >RIV/00064165:_____/23:10472577 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/23:10472577 RIV/44555601:13450/23:43899124

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=INuRzKu6Q2" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=INuRzKu6Q2</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.crad.2023.08.008" target="_blank" >10.1016/j.crad.2023.08.008</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Semi-automatic quantification of mosaic perfusion of lung parenchyma and its correlation with haemodynamic parameters in patients with chronic thromboembolic pulmonary hypertension

Popis výsledku v původním jazyce

AIM: To investigate the feasibility of semiautomatic quantification of mosaic perfusion and the associations between mosaic perfusion on computed tomography (CT; the ratio of hypo-perfused parenchyma to the whole lung volume) and haemodynamic parameters through linear regression analysis.MATERIALS AND METHODS: Fifty-eight consecutive patients (mean age 66 years, 28 fe -males) diagnosed with chronic thromboembolic pulmonary hypertension (CTEPH) in General University Hospital, Prague, in 2021 were evaluated retrospectively and underwent both right heart catheterisation and CT pulmonary angiography. The parameters derived from the CT examinations were correlated with the recorded haemodynamic parameters.RESULTS: A method was developed for semiautomatic detection of hypoperfused tissue from CT using widely available software and a statistically significant correlation was found between the proportion of hypoperfused parenchyma and the mean pulmonary artery pressure (mPAP; R-2 0.22; p&lt;0.01) and pulmonary vascular resistance (PVR; R-2 0.09; p&lt;0.05).CONCLUSIONS: The developed method facilitates the quantification of mosaic perfusion, which is associated with important haemodynamic parameters (mPAP and PVR) in patients with CTEPH.

Název v anglickém jazyce

Semi-automatic quantification of mosaic perfusion of lung parenchyma and its correlation with haemodynamic parameters in patients with chronic thromboembolic pulmonary hypertension

Popis výsledku anglicky

AIM: To investigate the feasibility of semiautomatic quantification of mosaic perfusion and the associations between mosaic perfusion on computed tomography (CT; the ratio of hypo-perfused parenchyma to the whole lung volume) and haemodynamic parameters through linear regression analysis.MATERIALS AND METHODS: Fifty-eight consecutive patients (mean age 66 years, 28 fe -males) diagnosed with chronic thromboembolic pulmonary hypertension (CTEPH) in General University Hospital, Prague, in 2021 were evaluated retrospectively and underwent both right heart catheterisation and CT pulmonary angiography. The parameters derived from the CT examinations were correlated with the recorded haemodynamic parameters.RESULTS: A method was developed for semiautomatic detection of hypoperfused tissue from CT using widely available software and a statistically significant correlation was found between the proportion of hypoperfused parenchyma and the mean pulmonary artery pressure (mPAP; R-2 0.22; p&lt;0.01) and pulmonary vascular resistance (PVR; R-2 0.09; p&lt;0.05).CONCLUSIONS: The developed method facilitates the quantification of mosaic perfusion, which is associated with important haemodynamic parameters (mPAP and PVR) in patients with CTEPH.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30224 - Radiology, nuclear medicine and medical imaging

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Clinical Radiology

ISSN

0009-9260

e-ISSN

1365-229X

Svazek periodika

78

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

"e918"-"e924"

Kód UT WoS článku

001109603700001

EID výsledku v databázi Scopus

2-s2.0-85169509159