Indications and outcomes of duodenum-preserving resection of the pancreatic head in children

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F19%3AN0000099" target="_blank" >RIV/00064173:_____/19:N0000099 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/19:10394265 RIV/00064203:_____/19:10394265

Výsledek na webu

<a href="https://doi.org/10.1007/s00383-018-4410-6" target="_blank" >https://doi.org/10.1007/s00383-018-4410-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00383-018-4410-6" target="_blank" >10.1007/s00383-018-4410-6</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Indications and outcomes of duodenum-preserving resection of the pancreatic head in children

Popis výsledku v původním jazyce

Aim of studyDuodenum-preserving resection of the pancreatic head (DPRPH) with Roux-en-Y pancreatojejunostomy is a procedure used to remove focal pathological lesions of the pancreatic head. Although predominantly used in adult patients, it is both safe and effective in children. The aim of this study was to review our experience with this procedure, with focus on its indications, complications and long-term outcomes.MethodsA retrospective analysis of pediatric patients who underwent DPRPH between 1994 and 2015 was performed. Patient files were reviewed for demographic, diagnostic, operative and histological details, postoperative complications. Patients were contacted telephonically and sent questionnaires to determine long-term outcomes.ResultsThe study cohort consists of 21 patients, 14 girls and 7 boys, with an average age of 11.72years (range 3months to 18.6years), who underwent DPRPH with end-to-end anastomosis of the jejunum to the pancreatic body (Roux-en-Y anastomosis). In four cases the head and also part of the body of the pancreas was resected. In the remaining 17 cases, only the head of the pancreas was resected. Indications for DPRPH were solid pseudopapillary tumor of the pancreas (n=10), trauma (n=8), pancreas divisum (n=1), focal congenital hyperinsulinism (n=1) and pancreatic cyst (n=1). The length of follow-up ranged from 1 to 22years (average 9.66). One patient developed a biliary fistula, which closed spontaneously within 2weeks after stent insertion. A recurrence of abdominal pain was reported in two patients, occurring at 7months after the operation in one patient and at 1year in the other. Pancreatic endocrine insufficiency did not occur in any of the 21 patients. Seven patients currently require a low fat diet, five of which need pancreatic enzyme supplementation. An additional two patients need enzyme supplementation without dietary restriction.ConclusionDPRPH is a safe and effective procedure for the treatment of large focal pathological lesions of the pancreatic head in children. As a less invasive procedure than pancreatoduodenectomy, it is more appropriate for the developing child.

Název v anglickém jazyce

Indications and outcomes of duodenum-preserving resection of the pancreatic head in children

Popis výsledku anglicky

Aim of studyDuodenum-preserving resection of the pancreatic head (DPRPH) with Roux-en-Y pancreatojejunostomy is a procedure used to remove focal pathological lesions of the pancreatic head. Although predominantly used in adult patients, it is both safe and effective in children. The aim of this study was to review our experience with this procedure, with focus on its indications, complications and long-term outcomes.MethodsA retrospective analysis of pediatric patients who underwent DPRPH between 1994 and 2015 was performed. Patient files were reviewed for demographic, diagnostic, operative and histological details, postoperative complications. Patients were contacted telephonically and sent questionnaires to determine long-term outcomes.ResultsThe study cohort consists of 21 patients, 14 girls and 7 boys, with an average age of 11.72years (range 3months to 18.6years), who underwent DPRPH with end-to-end anastomosis of the jejunum to the pancreatic body (Roux-en-Y anastomosis). In four cases the head and also part of the body of the pancreas was resected. In the remaining 17 cases, only the head of the pancreas was resected. Indications for DPRPH were solid pseudopapillary tumor of the pancreas (n=10), trauma (n=8), pancreas divisum (n=1), focal congenital hyperinsulinism (n=1) and pancreatic cyst (n=1). The length of follow-up ranged from 1 to 22years (average 9.66). One patient developed a biliary fistula, which closed spontaneously within 2weeks after stent insertion. A recurrence of abdominal pain was reported in two patients, occurring at 7months after the operation in one patient and at 1year in the other. Pancreatic endocrine insufficiency did not occur in any of the 21 patients. Seven patients currently require a low fat diet, five of which need pancreatic enzyme supplementation. An additional two patients need enzyme supplementation without dietary restriction.ConclusionDPRPH is a safe and effective procedure for the treatment of large focal pathological lesions of the pancreatic head in children. As a less invasive procedure than pancreatoduodenectomy, it is more appropriate for the developing child.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30212 - Surgery

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Pediatric Surgery International

ISSN

0179-0358

e-ISSN

1437-9813

Svazek periodika

35

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

7

Strana od-do

449-455

Kód UT WoS článku

000460667100007

EID výsledku v databázi Scopus

2-s2.0-85055988306