Celiac Disease and Liver Disorders: From Putative Pathogenesis to Clinical Implications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F19%3AN0000135" target="_blank" >RIV/00064173:_____/19:N0000135 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/19:43918094

Výsledek na webu

<a href="https://doi.org/10.3390/books978-3-03897-799-5" target="_blank" >https://doi.org/10.3390/books978-3-03897-799-5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/books978-3-03897-799-5" target="_blank" >10.3390/books978-3-03897-799-5</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Celiac Disease and Liver Disorders: From Putative Pathogenesis to Clinical Implications

Popis výsledku v původním jazyce

Immunologically mediated liver diseases belong to the common extraintestinal manifestations of celiac disease. We have reviewed the current literature that addresses the association between celiac disease and liver disorders. We searched relevant articles on MEDLINE/PubMed up to 15 June 2018. The objective of the article is to provide a comprehensive and up-to-date review on the latest hypotheses explaining the pathogenetic relationship between celiac disease and liver injury. Besides the involvement of gut–liver axis, tissue transglutaminase antibodies, and impairment of intestinal barrier, we integrate the latest achievements made in elucidation of the role of gut microbiota in celiac disease and liver disorders, that has not yet been sufficiently discussed in the literature in this context. The further objective is to provide a complete clinical overview on the types of liver diseases frequently found in celiac disease. In conclusion, the review highlights the clinical implication, recommend a rational approach for managing elevated transaminases in celiac patients, and underscore the importance of screening for celiac disease in patients with associated liver disease.

Název v anglickém jazyce

Celiac Disease and Liver Disorders: From Putative Pathogenesis to Clinical Implications

Popis výsledku anglicky

Immunologically mediated liver diseases belong to the common extraintestinal manifestations of celiac disease. We have reviewed the current literature that addresses the association between celiac disease and liver disorders. We searched relevant articles on MEDLINE/PubMed up to 15 June 2018. The objective of the article is to provide a comprehensive and up-to-date review on the latest hypotheses explaining the pathogenetic relationship between celiac disease and liver injury. Besides the involvement of gut–liver axis, tissue transglutaminase antibodies, and impairment of intestinal barrier, we integrate the latest achievements made in elucidation of the role of gut microbiota in celiac disease and liver disorders, that has not yet been sufficiently discussed in the literature in this context. The further objective is to provide a complete clinical overview on the types of liver diseases frequently found in celiac disease. In conclusion, the review highlights the clinical implication, recommend a rational approach for managing elevated transaminases in celiac patients, and underscore the importance of screening for celiac disease in patients with associated liver disease.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

30202 - Endocrinology and metabolism (including diabetes, hormones)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Extraintestinal Manifestations of Coeliac Disease

ISBN

978-3-03897-798-8

Počet stran výsledku

17

Strana od-do

134-150

Počet stran knihy

206

Název nakladatele

MDPI

Místo vydání

Basel

Kód UT WoS kapitoly

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