Gait festination in parkinsonism: introduction of two phenotypes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F19%3AN0000185" target="_blank" >RIV/00064173:_____/19:N0000185 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/19:10385497 RIV/00216208:11120/19:43917427 RIV/00064165:_____/19:10385497

Výsledek na webu

<a href="https://doi.org/10.1007/s00415-018-9146-7" target="_blank" >https://doi.org/10.1007/s00415-018-9146-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00415-018-9146-7" target="_blank" >10.1007/s00415-018-9146-7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Gait festination in parkinsonism: introduction of two phenotypes

Popis výsledku v původním jazyce

Gait festination is one of the most characteristic gait disturbances in patients with Parkinson's disease or atypical parkinson-ism. Although festination is common and disabling, it has received little attention in the literature, and different definitions exist. Here, we argue that there are actually two phenotypes of festination. The first phenotype entails a primary locomotion disturbance, due to the so-called sequence effect: a progressive shortening of step length, accompanied by a compensatory increase in cadence. This phenotype strongly relates to freezing of gait with alternating trembling of the leg. The second phenotype results from a postural control problem (forward leaning of the trunk) combined with a balance control deficit (inappropriately small balance-correcting steps). In this viewpoint, we elaborate on the possible pathophysiological substrate of these two phenotypes of festination and discuss their management in daily clinical practice.

Název v anglickém jazyce

Gait festination in parkinsonism: introduction of two phenotypes

Popis výsledku anglicky

Gait festination is one of the most characteristic gait disturbances in patients with Parkinson's disease or atypical parkinson-ism. Although festination is common and disabling, it has received little attention in the literature, and different definitions exist. Here, we argue that there are actually two phenotypes of festination. The first phenotype entails a primary locomotion disturbance, due to the so-called sequence effect: a progressive shortening of step length, accompanied by a compensatory increase in cadence. This phenotype strongly relates to freezing of gait with alternating trembling of the leg. The second phenotype results from a postural control problem (forward leaning of the trunk) combined with a balance control deficit (inappropriately small balance-correcting steps). In this viewpoint, we elaborate on the possible pathophysiological substrate of these two phenotypes of festination and discuss their management in daily clinical practice.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30210 - Clinical neurology

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Neurology

ISSN

0340-5354

e-ISSN

1432-1459

Svazek periodika

266

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

5

Strana od-do

426-430

Kód UT WoS článku

000458151200017

EID výsledku v databázi Scopus

2-s2.0-85058039126