Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F23%3A43925387" target="_blank" >RIV/00064173:_____/23:43925387 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/23:43925387

Výsledek na webu

<a href="https://doi.org/10.1684/ejd.2023.4402" target="_blank" >https://doi.org/10.1684/ejd.2023.4402</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1684/ejd.2023.4402" target="_blank" >10.1684/ejd.2023.4402</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis

Popis výsledku v původním jazyce

Seborrheic Dermatitis (SD) is a chronic and relapsing inflammatory condition accompanied by erythema, flaking and itching. Dandruff is a milder form of SD. Selenium disulfide (SeS2) is beneficial in both conditions. OBJECTIVES: to assess the efficacy of SeS2-based shampoo in dandruff/SD. MATERIALS &amp; METHODS: an international, multicenter, observational study was conducted in 1407 adult subjects. SeS2- based shampoo was used 2 to 3 times per week for 4 weeks. Clinical efficacy criteria included improvement of hair, flaking, erythema and irritation on a scale from 0 to 5; investigator satisfaction was assessed at month 3 from 0 to 10. The subjects rated the impact of their hair problem (0 to 5), efficacy and satisfaction with SeS2-based shampoo at month 3. Tolerance was assessed throughout the study. RESULTS: At baseline, 68.2% had a flake severity score of 3-5, 49.9% an erythema severity score of 3-5, and 46.2% an irritation severity score of 3-5; 28.2% were bothered and 41.5% were very bothered. At study end, SD/D had at least clearly improved in 89.6% of subjects. All clinical signs had significantly (p&lt;0.001) improved. 95.6% of subjects reported less pruritus. Significantly fewer (15.4%, p&lt;0.0001) subjects were still bothered. The overall subject satisfaction score was 8.9+-1.4; 97.6% of investigators were satisfied or very satisfied. Tolerance was good or very good in 98.8% of subjects. CONCLUSION: A SeS2-based shampoo applied 2 to 3 times per week is efficient and well tolerated in dandruff and SD.

Název v anglickém jazyce

Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis

Popis výsledku anglicky

Seborrheic Dermatitis (SD) is a chronic and relapsing inflammatory condition accompanied by erythema, flaking and itching. Dandruff is a milder form of SD. Selenium disulfide (SeS2) is beneficial in both conditions. OBJECTIVES: to assess the efficacy of SeS2-based shampoo in dandruff/SD. MATERIALS &amp; METHODS: an international, multicenter, observational study was conducted in 1407 adult subjects. SeS2- based shampoo was used 2 to 3 times per week for 4 weeks. Clinical efficacy criteria included improvement of hair, flaking, erythema and irritation on a scale from 0 to 5; investigator satisfaction was assessed at month 3 from 0 to 10. The subjects rated the impact of their hair problem (0 to 5), efficacy and satisfaction with SeS2-based shampoo at month 3. Tolerance was assessed throughout the study. RESULTS: At baseline, 68.2% had a flake severity score of 3-5, 49.9% an erythema severity score of 3-5, and 46.2% an irritation severity score of 3-5; 28.2% were bothered and 41.5% were very bothered. At study end, SD/D had at least clearly improved in 89.6% of subjects. All clinical signs had significantly (p&lt;0.001) improved. 95.6% of subjects reported less pruritus. Significantly fewer (15.4%, p&lt;0.0001) subjects were still bothered. The overall subject satisfaction score was 8.9+-1.4; 97.6% of investigators were satisfied or very satisfied. Tolerance was good or very good in 98.8% of subjects. CONCLUSION: A SeS2-based shampoo applied 2 to 3 times per week is efficient and well tolerated in dandruff and SD.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

30216 - Dermatology and venereal diseases

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Dermatology

ISSN

1167-1122

e-ISSN

1952-4013

Svazek periodika

33

Číslo periodika v rámci svazku

Suppl. 1

Stát vydavatele periodika

FR - Francouzská republika

Počet stran výsledku

5

Strana od-do

19-23

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85153983426