Evaluating the Impact of an Anti-Microbial Silver-Impregnated Surgical Dressing on Wound Infections and Healing: A Randomized Clinical Trial

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F24%3A43926246" target="_blank" >RIV/00064173:_____/24:43926246 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/24:43926246

Výsledek na webu

<a href="https://doi.org/10.1111/wrr.13142" target="_blank" >https://doi.org/10.1111/wrr.13142</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/wrr.13142" target="_blank" >10.1111/wrr.13142</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Evaluating the Impact of an Anti-Microbial Silver-Impregnated Surgical Dressing on Wound Infections and Healing: A Randomized Clinical Trial

Popis výsledku v původním jazyce

StopBac is an innovative silver-impregnated antimicrobial dressing specifically designed to reduce surgical site infections and enhance healing. The primary objective of this study was to compare infection rate and healing rate at the 30 days after surgery between primarily closed surgical wounds covered with StopBac and those covered with Cosmorpor, a standard surgical dressing. Between 1.3.2023 and 30.4.2023, we conducted a prospective screening of all patients undergoing surgical operations within a single surgical department. Patients were randomized into either the Cosmopor group or the StopBac group. Outcome measures were superficial and deep surgical site infections and healed wounds. Data concerning demographic, patients and surgical factors were prospectively collected and analysed. The analysis comprised 275 patients, divided into two groups: 140 patients in the StopBac group and 135 in the control group. StopBac dressing was associated with a reduced rate of infection, with an odds ratio of 0.288 (p&lt;0.001), and an increased likelihood of wound healing by 30 days after surgery. The odds ratio for healing at 30 days was 4.661 (p&lt;0.001). The surgical dressing StopBac was associated with a lower incidence of surgical wound infections and a higher probability of healing at 30 days after surgery, when compared with standard dressing.

Název v anglickém jazyce

Evaluating the Impact of an Anti-Microbial Silver-Impregnated Surgical Dressing on Wound Infections and Healing: A Randomized Clinical Trial

Popis výsledku anglicky

StopBac is an innovative silver-impregnated antimicrobial dressing specifically designed to reduce surgical site infections and enhance healing. The primary objective of this study was to compare infection rate and healing rate at the 30 days after surgery between primarily closed surgical wounds covered with StopBac and those covered with Cosmorpor, a standard surgical dressing. Between 1.3.2023 and 30.4.2023, we conducted a prospective screening of all patients undergoing surgical operations within a single surgical department. Patients were randomized into either the Cosmopor group or the StopBac group. Outcome measures were superficial and deep surgical site infections and healed wounds. Data concerning demographic, patients and surgical factors were prospectively collected and analysed. The analysis comprised 275 patients, divided into two groups: 140 patients in the StopBac group and 135 in the control group. StopBac dressing was associated with a reduced rate of infection, with an odds ratio of 0.288 (p&lt;0.001), and an increased likelihood of wound healing by 30 days after surgery. The odds ratio for healing at 30 days was 4.661 (p&lt;0.001). The surgical dressing StopBac was associated with a lower incidence of surgical wound infections and a higher probability of healing at 30 days after surgery, when compared with standard dressing.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30212 - Surgery

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Wound Repair and Regeneration

ISSN

1067-1927

e-ISSN

1524-475X

Svazek periodika

32

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

67-73

Kód UT WoS článku

001136975500001

EID výsledku v databázi Scopus

2-s2.0-85181502581