Maintaining kidney health in aging societies: a JSN and ERA call to action

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F25%3A43928356" target="_blank" >RIV/00064173:_____/25:43928356 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/25:43928356

Výsledek na webu

<a href="https://doi.org/10.1093/ndt/gfaf068" target="_blank" >https://doi.org/10.1093/ndt/gfaf068</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/ndt/gfaf068" target="_blank" >10.1093/ndt/gfaf068</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Maintaining kidney health in aging societies: a JSN and ERA call to action

Popis výsledku v původním jazyce

Chronic kidney disease (CKD) is the fastest growing cause of death, expected to become the fifth global cause of death and the third in some countries with long life expectancy, such as Japan and Spain by 2050. This reflects societal aging, as advancing kidney age is the main risk factor for CKD. The forecasted 140% increase in death rate from CKD by 2050 is reduced to 33% when adjusted for age. The increasing mortality burden is paralleled by higher personal, healthcare, socioeconomic, and environmental burdens and need for kidney replacement therapy to treat kidney failure. To some extent, the higher CKD burden represents the price of success in prolonging longevity by decreasing other causes of death. Now is the time to act to minimize the negative impact of CKD on aging societies through primary prevention and early diagnosis and treatment of CKD. Action aimed at maintaining kidney health and delaying kidney aging will contribute to healthy aging as the kidneys have gerosuppressor functions. CKD has the highest negative impact on body aging among chronic non-communicable diseases. This should be part of a move towards novel holistic approaches to healthy longevity represented by concepts such as cardiovascular-kidney-metabolic health, geromedicine, gerosuppressors, and organ rejuvenation. We discuss a conceptual framework for the present and future of kidney aging and kidney health in the elderly, emphasizing opportunities for intervention that underlie the Japanese Society of Nephrology (JSN) and European Renal Association (ERA) call to action on Achieving Kidney Health in Aging/Aged Societies.

Název v anglickém jazyce

Maintaining kidney health in aging societies: a JSN and ERA call to action

Popis výsledku anglicky

Chronic kidney disease (CKD) is the fastest growing cause of death, expected to become the fifth global cause of death and the third in some countries with long life expectancy, such as Japan and Spain by 2050. This reflects societal aging, as advancing kidney age is the main risk factor for CKD. The forecasted 140% increase in death rate from CKD by 2050 is reduced to 33% when adjusted for age. The increasing mortality burden is paralleled by higher personal, healthcare, socioeconomic, and environmental burdens and need for kidney replacement therapy to treat kidney failure. To some extent, the higher CKD burden represents the price of success in prolonging longevity by decreasing other causes of death. Now is the time to act to minimize the negative impact of CKD on aging societies through primary prevention and early diagnosis and treatment of CKD. Action aimed at maintaining kidney health and delaying kidney aging will contribute to healthy aging as the kidneys have gerosuppressor functions. CKD has the highest negative impact on body aging among chronic non-communicable diseases. This should be part of a move towards novel holistic approaches to healthy longevity represented by concepts such as cardiovascular-kidney-metabolic health, geromedicine, gerosuppressors, and organ rejuvenation. We discuss a conceptual framework for the present and future of kidney aging and kidney health in the elderly, emphasizing opportunities for intervention that underlie the Japanese Society of Nephrology (JSN) and European Renal Association (ERA) call to action on Achieving Kidney Health in Aging/Aged Societies.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30217 - Urology and nephrology

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Nephrology, Dialysis, Transplantation

ISSN

0931-0509

e-ISSN

1460-2385

Svazek periodika

40

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

14

Strana od-do

1498-1511

Kód UT WoS článku

001497479200001

EID výsledku v databázi Scopus

2-s2.0-105012508460