Postoperative quality of life in patients with early-stage cervical cancer: A prospective 10-year follow-up study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F25%3A43928411" target="_blank" >RIV/00064173:_____/25:43928411 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/25:43928411 RIV/00216208:11130/25:10497816 RIV/00064203:_____/25:10497816

Výsledek na webu

<a href="https://doi.org/10.1016/j.ejso.2025.110119" target="_blank" >https://doi.org/10.1016/j.ejso.2025.110119</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ejso.2025.110119" target="_blank" >10.1016/j.ejso.2025.110119</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Postoperative quality of life in patients with early-stage cervical cancer: A prospective 10-year follow-up study

Popis výsledku v původním jazyce

INTRODUCTION: The substantial improvement in early-stage cervical cancer survival rates has given rise to the significance of subsequent quality of life. This study aims to assess the quality of life in patients subjected to radical and conservative surgeries for cervical cancer. MATERIALS AND METHODS: One hundred patients diagnosed with early-stage cervical cancer (stages IA2-IIA1) undergoing surgical treatment were enrolled in our study between 2007 and 2011. Patients completed quality of life questionnaires EORTC QLQ-C30 and QLQ-CX24, distributed before the surgery, 6, 12, and 120 months after the procedure. At the final 120-month follow-up, 54 patients remained eligible for inclusion. 23 patients (&quot;CONS group&quot;) underwent laparoscopic lymphadenectomy combined with hysterectomy or simple trachelectomy. The remaining 31 patients (&quot;RAD group&quot;) underwent abdominal radical hysterectomy type C1. RESULTS: At the 6-month post-surgery assessment, the RAD group reported a significantly higher incidence of menopausal symptoms, decline in physical functioning and concern regarding their sexual well-being. CONS group patients reported notable exacerbation of lymphedema and neuropathy-related symptoms but only a slight decline in physical functioning. Additionally, their role functioning, emotional well-being, and social functioning significantly improved compared to their preoperative baseline. At the 120-month postoperative assessment the RAD group showed a significant decline in several parameters, including lymphedema, peripheral neuropathy, postmenopausal symptoms, fatigue, pain, and physical functioning. CONCLUSIONS: Cervical cancer treatment is invariably associated with a negative long-term impact on quality of life, RAD group demonstrated poorer outcomes than the CONS group across multiple parameters but even the CONS group exhibited long-term effects of the surgery.

Název v anglickém jazyce

Postoperative quality of life in patients with early-stage cervical cancer: A prospective 10-year follow-up study

Popis výsledku anglicky

INTRODUCTION: The substantial improvement in early-stage cervical cancer survival rates has given rise to the significance of subsequent quality of life. This study aims to assess the quality of life in patients subjected to radical and conservative surgeries for cervical cancer. MATERIALS AND METHODS: One hundred patients diagnosed with early-stage cervical cancer (stages IA2-IIA1) undergoing surgical treatment were enrolled in our study between 2007 and 2011. Patients completed quality of life questionnaires EORTC QLQ-C30 and QLQ-CX24, distributed before the surgery, 6, 12, and 120 months after the procedure. At the final 120-month follow-up, 54 patients remained eligible for inclusion. 23 patients (&quot;CONS group&quot;) underwent laparoscopic lymphadenectomy combined with hysterectomy or simple trachelectomy. The remaining 31 patients (&quot;RAD group&quot;) underwent abdominal radical hysterectomy type C1. RESULTS: At the 6-month post-surgery assessment, the RAD group reported a significantly higher incidence of menopausal symptoms, decline in physical functioning and concern regarding their sexual well-being. CONS group patients reported notable exacerbation of lymphedema and neuropathy-related symptoms but only a slight decline in physical functioning. Additionally, their role functioning, emotional well-being, and social functioning significantly improved compared to their preoperative baseline. At the 120-month postoperative assessment the RAD group showed a significant decline in several parameters, including lymphedema, peripheral neuropathy, postmenopausal symptoms, fatigue, pain, and physical functioning. CONCLUSIONS: Cervical cancer treatment is invariably associated with a negative long-term impact on quality of life, RAD group demonstrated poorer outcomes than the CONS group across multiple parameters but even the CONS group exhibited long-term effects of the surgery.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30204 - Oncology

Projekt

<a href="/cs/project/NW24-09-00505" target="_blank" >NW24-09-00505: Molekulární klasifikace ve vztahu k prevenci rekurence karcinomu endometria a life style faktorům</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Surgical Oncology

ISSN

0748-7983

e-ISSN

1532-2157

Svazek periodika

51

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

110119

Kód UT WoS článku

001490840700002

EID výsledku v databázi Scopus

2-s2.0-105004468959