RESULTS OF TREATMENT OF THE MULTIDRUG RESISTANT TUBERCULOSIS

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F03%3A%230001182" target="_blank" >RIV/00064190:_____/03:#0001182 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

RESULTS OF TREATMENT OF THE MULTIDRUG RESISTANT TUBERCULOSIS

Popis výsledku v původním jazyce

Multidrug resistant tuberculosis (MDR TB) is an infectious disease with limited therapeutic possibilities.Beside its epidemiological importance, MDR TB represents a problem also for long-term therapy withantituberculous drug combination and for its economical costs.Methods and Results. We evaluated retrospectively the effect of treatment of MDR TB according to the clinical,radiological and bacteriological findings of 11 patients hospitalised in our department in years 1996 to 2000.Individual chemotherapy regimens were chosen according to the susceptibility test results for the first and second-lineantituberculosis drugs. Despite the fully controlled and long-term treatment, seven patients died during the regimen;in three of them the cause of death was different from MDR TB.Conclusions. Prevalence of MDR TB cases in the Czech republic has remained in the same level for several previousyears and it represents about 20–30 persons. To prevent acquired resistance with its negative consequences, it wouldbe optimal to implement the recommended standardized treatment regimens.

Název v anglickém jazyce

RESULTS OF TREATMENT OF THE MULTIDRUG RESISTANT TUBERCULOSIS

Popis výsledku anglicky

Multidrug resistant tuberculosis (MDR TB) is an infectious disease with limited therapeutic possibilities.Beside its epidemiological importance, MDR TB represents a problem also for long-term therapy withantituberculous drug combination and for its economical costs.Methods and Results. We evaluated retrospectively the effect of treatment of MDR TB according to the clinical,radiological and bacteriological findings of 11 patients hospitalised in our department in years 1996 to 2000.Individual chemotherapy regimens were chosen according to the susceptibility test results for the first and second-lineantituberculosis drugs. Despite the fully controlled and long-term treatment, seven patients died during the regimen;in three of them the cause of death was different from MDR TB.Conclusions. Prevalence of MDR TB cases in the Czech republic has remained in the same level for several previousyears and it represents about 20–30 persons. To prevent acquired resistance with its negative consequences, it wouldbe optimal to implement the recommended standardized treatment regimens.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FC - Pneumologie

OECD FORD obor

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Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2003

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Časopis lékařů českých

ISSN

0008-7335

e-ISSN

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Svazek periodika

142

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

3

Strana od-do

226-228

Kód UT WoS článku

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EID výsledku v databázi Scopus

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