Evaluation of Cortical Activity Associated with Filling of Urinary Bladder Using Functional Magnetic Resonance Imaging

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F13%3A%230000474" target="_blank" >RIV/00064190:_____/13:#0000474 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064190:_____/13:#0000606

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Evaluation of Cortical Activity Associated with Filling of Urinary Bladder Using Functional Magnetic Resonance Imaging

Popis výsledku v původním jazyce

The aim of the study was to assess: 1. the feasibility of a novel method combining functional magnetic resonance imaging (fMRI) evaluation of the central nervous system (CNS) with synchronously performed filling cystometry, 2. fMRI evaluation of brain cortical activity associated with filling of the urinary bladder. Methods: A urodynamic system was adapted to enable synchronous filling cystometry with fMRI. Fourteen female volunteers with no urological disorder (20-68 yrs) were enrolled. Standard filling cystometry protocol was extended to strengthen the afferent sensory signal: the sensory activation was elicited by cyclic phases of filling and emptying. Synchronously with extended cystometry, cortical activity was evaluated using fMRI. To yield representative data, we repeated each examination after 4-6 weeks having 28 data sets for analysis at the end. All examinations were performed on 31 scanner (Siemens Trio) using gradient-echo EPI sequence with the following parameters: TE = 30

Název v anglickém jazyce

Evaluation of Cortical Activity Associated with Filling of Urinary Bladder Using Functional Magnetic Resonance Imaging

Popis výsledku anglicky

The aim of the study was to assess: 1. the feasibility of a novel method combining functional magnetic resonance imaging (fMRI) evaluation of the central nervous system (CNS) with synchronously performed filling cystometry, 2. fMRI evaluation of brain cortical activity associated with filling of the urinary bladder. Methods: A urodynamic system was adapted to enable synchronous filling cystometry with fMRI. Fourteen female volunteers with no urological disorder (20-68 yrs) were enrolled. Standard filling cystometry protocol was extended to strengthen the afferent sensory signal: the sensory activation was elicited by cyclic phases of filling and emptying. Synchronously with extended cystometry, cortical activity was evaluated using fMRI. To yield representative data, we repeated each examination after 4-6 weeks having 28 data sets for analysis at the end. All examinations were performed on 31 scanner (Siemens Trio) using gradient-echo EPI sequence with the following parameters: TE = 30

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Česká a slovenská neurologie a neurochirurgie

ISSN

1210-7859

e-ISSN

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Svazek periodika

76

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

45-51

Kód UT WoS článku

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EID výsledku v databázi Scopus

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