Occipitocervical stabilization using bilateral laminar C2 screws in children with mucopolysaccharidosis IVA

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F15%3A%230001124" target="_blank" >RIV/00064190:_____/15:#0001124 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61383082:_____/15:#0000385 RIV/00216208:11110/15:10314193 RIV/00216208:11120/15:43910306 RIV/00064165:_____/15:10314193

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00586-015-3879-0" target="_blank" >http://dx.doi.org/10.1007/s00586-015-3879-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00586-015-3879-0" target="_blank" >10.1007/s00586-015-3879-0</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Occipitocervical stabilization using bilateral laminar C2 screws in children with mucopolysaccharidosis IVA

Popis výsledku v původním jazyce

Mucopolysaccharidosis IVA (MPS IVA) is a multisystemic storage disorder. Patient's disability and life expectancy depends upon skeletal complications, including cervical myelopathy due to upper cervical compression or instability. Posterior decompression followed by occipitocervical fixation or C1-2 fusion are the most frequently recommended surgical interventions. The bony elements of C1 and C2 are often inadequately developed making routine screw insertion difficult. The main purpose of this work was to present novel technique of occipitocervical fixation using two C2 laminar screws. Four children with MPS IVA underwent decompression and C0-C2 instrumented fusion using two C2 bilateral laminar screws. The dimensions of the C2 lamina were measured. Clinical and radiological results were monitored prospectively for a minimum 3 years. The mean laminar length was 24 +/- A 1.15 mm, width 6.15 +/- A 0.55 mm and height 7.4 +/- A 0.6 mm. Patients remained in a stable neurological condition. The mean antero-posterior diameter of the spinal canal on the pre-operative MR was 6.2 +/- A 0.74 mm and it was enlarged to 11.4 +/- A 0.8 mm after 3 years. All screws were placed adequately. In all patients, the control CT scan 2 years post-operatively revealed a stable position of the treated segments, but solid bony fusion was not registered in any patient. Decompression and fusion of the upper cervical spine is a generally accepted approach to treat upper cervical spine instability and myelopathy in MPS IVA patients. The feasibility and the suitability of the technique of C0-C2 stabilization using bilateral C2 laminar screws have been presented.

Název v anglickém jazyce

Occipitocervical stabilization using bilateral laminar C2 screws in children with mucopolysaccharidosis IVA

Popis výsledku anglicky

Mucopolysaccharidosis IVA (MPS IVA) is a multisystemic storage disorder. Patient's disability and life expectancy depends upon skeletal complications, including cervical myelopathy due to upper cervical compression or instability. Posterior decompression followed by occipitocervical fixation or C1-2 fusion are the most frequently recommended surgical interventions. The bony elements of C1 and C2 are often inadequately developed making routine screw insertion difficult. The main purpose of this work was to present novel technique of occipitocervical fixation using two C2 laminar screws. Four children with MPS IVA underwent decompression and C0-C2 instrumented fusion using two C2 bilateral laminar screws. The dimensions of the C2 lamina were measured. Clinical and radiological results were monitored prospectively for a minimum 3 years. The mean laminar length was 24 +/- A 1.15 mm, width 6.15 +/- A 0.55 mm and height 7.4 +/- A 0.6 mm. Patients remained in a stable neurological condition. The mean antero-posterior diameter of the spinal canal on the pre-operative MR was 6.2 +/- A 0.74 mm and it was enlarged to 11.4 +/- A 0.8 mm after 3 years. All screws were placed adequately. In all patients, the control CT scan 2 years post-operatively revealed a stable position of the treated segments, but solid bony fusion was not registered in any patient. Decompression and fusion of the upper cervical spine is a generally accepted approach to treat upper cervical spine instability and myelopathy in MPS IVA patients. The feasibility and the suitability of the technique of C0-C2 stabilization using bilateral C2 laminar screws have been presented.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

EUROPEAN SPINE JOURNAL

ISSN

0940-6719

e-ISSN

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Svazek periodika

24

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

2756-2762

Kód UT WoS článku

000365875800007

EID výsledku v databázi Scopus

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