Cancer detection rates and inter-examiner variability of MRI/TRUS fusion targeted biopsy and systematic transrectal biopsy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F19%3AN0000130" target="_blank" >RIV/00064190:_____/19:N0000130 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/20:10414590 RIV/00216208:11120/20:43920523 RIV/00216208:11130/20:10414590 RIV/00064203:_____/20:10414590 RIV/00064190:_____/20:N0000044

Výsledek na webu

<a href="https://biomed.papers.upol.cz/getrevsrc.php?identification=public&mag=bio&raid=2137&type=fin&ver=3" target="_blank" >https://biomed.papers.upol.cz/getrevsrc.php?identification=public&mag=bio&raid=2137&type=fin&ver=3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2019.050" target="_blank" >10.5507/bp.2019.050</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cancer detection rates and inter-examiner variability of MRI/TRUS fusion targeted biopsy and systematic transrectal biopsy

Popis výsledku v původním jazyce

Background: Software-based MRI/TRUS fusion biopsy depends on the coordination of several steps, and inter-examiner differences could influence the results. The aim of this bicentric prospective study was to compare the detection rates of MRI/TRUS fusion targeted biopsy (TG) and systematic biopsy (SB), and the detection rates of examiners with different levels of previous experience in prostate biopsy. Methods: A total of 419 patients underwent MRI based on a suspicion of prostate cancer with elevated PSA levels. MRI was positive in 395 patients (221 in the first biopsy group [FB] and 174 in the repeated biopsy group [RB]). A subsequent TG, followed by a SB, was performed on these patients by four different examiners. Results: In the detection of clinically significant prostate cancer, a significant difference was found for TG+SB against SB in the RB group (35.1% vs. 25.3%, P=0.047). In the detection of clinically insignificant prostate cancer, the SB had a significantly higher detection rate than TG in both subgroups (FB: 11.9% vs. 4.7%, P=0.008; RB: 13.8% vs. 6.9%, P=0.034). A significant difference was found between the four examiners in the FB for TG (P=0.028), SB (P=0.036), and TG+SB (P=0.017). Conclusion: MRI/TRUS TG in combination with SB had significantly higher detection rates than SB in the RB group only. Differences in detection rates between examiners were dependent on the level of previous experience with TRUS guided biopsy.

Název v anglickém jazyce

Cancer detection rates and inter-examiner variability of MRI/TRUS fusion targeted biopsy and systematic transrectal biopsy

Popis výsledku anglicky

Background: Software-based MRI/TRUS fusion biopsy depends on the coordination of several steps, and inter-examiner differences could influence the results. The aim of this bicentric prospective study was to compare the detection rates of MRI/TRUS fusion targeted biopsy (TG) and systematic biopsy (SB), and the detection rates of examiners with different levels of previous experience in prostate biopsy. Methods: A total of 419 patients underwent MRI based on a suspicion of prostate cancer with elevated PSA levels. MRI was positive in 395 patients (221 in the first biopsy group [FB] and 174 in the repeated biopsy group [RB]). A subsequent TG, followed by a SB, was performed on these patients by four different examiners. Results: In the detection of clinically significant prostate cancer, a significant difference was found for TG+SB against SB in the RB group (35.1% vs. 25.3%, P=0.047). In the detection of clinically insignificant prostate cancer, the SB had a significantly higher detection rate than TG in both subgroups (FB: 11.9% vs. 4.7%, P=0.008; RB: 13.8% vs. 6.9%, P=0.034). A significant difference was found between the four examiners in the FB for TG (P=0.028), SB (P=0.036), and TG+SB (P=0.017). Conclusion: MRI/TRUS TG in combination with SB had significantly higher detection rates than SB in the RB group only. Differences in detection rates between examiners were dependent on the level of previous experience with TRUS guided biopsy.

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

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OECD FORD obor

30204 - Oncology

Projekt

<a href="/cs/project/NV15-27047A" target="_blank" >NV15-27047A: Využití fúzní magnetické rezonance a transrektální ultrasonografie pro detekci karcinomu prostaty</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia

ISSN

1213-8118

e-ISSN

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Svazek periodika

neuveden

Číslo periodika v rámci svazku

10/2019 online

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

nestránkovano

Kód UT WoS článku

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EID výsledku v databázi Scopus

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