Primary progressive aphasia

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F20%3AN0000099" target="_blank" >RIV/00064190:_____/20:N0000099 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.14735/amcsnn2020226" target="_blank" >http://dx.doi.org/10.14735/amcsnn2020226</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14735/amcsnn2020226" target="_blank" >10.14735/amcsnn2020226</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Primary progressive aphasia

Popis výsledku v původním jazyce

Primary progressive aphasia (PPA) results from selective neurodegeneration mainly in the areas of the language-dominant hemisphere, disrupting processes whose proper functioning is ensured by a complex language network in the brain, localized mainly in the cortex but also in subcortical and deeper brain areas. Speech/language deficits are the first and long-term dominant problem in the initial stage of the disease, causing significant impairment in activities of everyday life in PPA patients. We summarize the most important aspects of PPA with special emphasis on the characteristics of three PPA variants - the nonfluent/agrammatic, semantic and logopenic variants and primary apraxia of speech are described in terms of linguistic deficits and co-occurring cognitive disorders (neuropsychological aspects) and neuropsychiatric disorders, especially behavioral disorders. We provide information that can help to identify key symptoms more rapidly in clinical practice. The clinical picture of PPA is complemented by localization of brain atrophy on MRI and also by summarizing specific PPA neuropathology

Název v anglickém jazyce

Primary progressive aphasia

Popis výsledku anglicky

Primary progressive aphasia (PPA) results from selective neurodegeneration mainly in the areas of the language-dominant hemisphere, disrupting processes whose proper functioning is ensured by a complex language network in the brain, localized mainly in the cortex but also in subcortical and deeper brain areas. Speech/language deficits are the first and long-term dominant problem in the initial stage of the disease, causing significant impairment in activities of everyday life in PPA patients. We summarize the most important aspects of PPA with special emphasis on the characteristics of three PPA variants - the nonfluent/agrammatic, semantic and logopenic variants and primary apraxia of speech are described in terms of linguistic deficits and co-occurring cognitive disorders (neuropsychological aspects) and neuropsychiatric disorders, especially behavioral disorders. We provide information that can help to identify key symptoms more rapidly in clinical practice. The clinical picture of PPA is complemented by localization of brain atrophy on MRI and also by summarizing specific PPA neuropathology

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

<a href="/cs/project/NV19-04-00090" target="_blank" >NV19-04-00090: Překrývání neurodegenerativních demencí a jejich klinickopatologické korelace: prospektivně-retrospektivní multicentrická studie</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ČESKÁ A SLOVENSKÁ NEUROLOGIE A NEUROCHIRURGIE

ISSN

1210-7859

e-ISSN

1802-4041

Svazek periodika

83

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

14

Strana od-do

226-239

Kód UT WoS článku

000571508700001

EID výsledku v databázi Scopus

2-s2.0-85089624544