Prevalence and mortality in children with congenital diaphragmatic hernia: a multicountry study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F20%3AN0000120" target="_blank" >RIV/00064190:_____/20:N0000120 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.annepidem.2020.11.007" target="_blank" >http://dx.doi.org/10.1016/j.annepidem.2020.11.007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.annepidem.2020.11.007" target="_blank" >10.1016/j.annepidem.2020.11.007</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Prevalence and mortality in children with congenital diaphragmatic hernia: a multicountry study

Popis výsledku v původním jazyce

Purpose: This study determined the prevalence, mortality, and time trends of children with congenital diaphragmatic hernia (CDH). Methods: Twenty-five hospital- and population-based surveillance programs in 19 International Clearinghouse for Birth Defects Surveillance and Research member countries provided birth defects mortality data between 1974 and 2015. CDH cases included live births, stillbirths, or elective termination of pregnancy for fetal anomalies. Prevalence, cumulative mortality rates, and 95% confidence intervals (CIs) were calculated using Poisson regression and a Kaplan–Meier product-limit method. Joinpoint regression analyses were conducted to assess time trends. Results: The prevalence of CDH was 2.6 per 10,000 total births (95% CI: 2.5–2.7), slightly increasing between 2001 and 2012 (average annual percent change = 0.5%; 95% CI:−0.6 to 1.6). The total percent mortality of CDH was 37.7%, with hospital-based registries having more deaths among live births than population-based registries (45.1% vs. 33.8%). Mortality rates decreased over time (average annual percent change = −2.4%; 95% CI: −3.8 to 1.1). Most deaths due to CDH occurred among 2- to 6-day-old infants for both registry types (36.3%, hospital-based; 12.1%, population-based). Conclusions: The mortality of CDH has decreased over time. Mortality remains high during the first week and varied by registry type.

Název v anglickém jazyce

Prevalence and mortality in children with congenital diaphragmatic hernia: a multicountry study

Popis výsledku anglicky

Purpose: This study determined the prevalence, mortality, and time trends of children with congenital diaphragmatic hernia (CDH). Methods: Twenty-five hospital- and population-based surveillance programs in 19 International Clearinghouse for Birth Defects Surveillance and Research member countries provided birth defects mortality data between 1974 and 2015. CDH cases included live births, stillbirths, or elective termination of pregnancy for fetal anomalies. Prevalence, cumulative mortality rates, and 95% confidence intervals (CIs) were calculated using Poisson regression and a Kaplan–Meier product-limit method. Joinpoint regression analyses were conducted to assess time trends. Results: The prevalence of CDH was 2.6 per 10,000 total births (95% CI: 2.5–2.7), slightly increasing between 2001 and 2012 (average annual percent change = 0.5%; 95% CI:−0.6 to 1.6). The total percent mortality of CDH was 37.7%, with hospital-based registries having more deaths among live births than population-based registries (45.1% vs. 33.8%). Mortality rates decreased over time (average annual percent change = −2.4%; 95% CI: −3.8 to 1.1). Most deaths due to CDH occurred among 2- to 6-day-old infants for both registry types (36.3%, hospital-based; 12.1%, population-based). Conclusions: The mortality of CDH has decreased over time. Mortality remains high during the first week and varied by registry type.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

30101 - Human genetics

Projekt

<a href="/cs/project/NV17-29622A" target="_blank" >NV17-29622A: Analýza efektivity prenatální diagnostiky vrozených vad a přežívání dětí narozených s vrozenou vadou v České republice v období 1994 – 2015</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Annals of Epidemiology

ISSN

1047-2797

e-ISSN

1873-2585

Svazek periodika

56

Číslo periodika v rámci svazku

April 2021

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

61-69

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85098163350