Impaired awareness of hypoglycemia in a study protocol

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F21%3AN0000021" target="_blank" >RIV/00064190:_____/21:N0000021 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064203:_____/21:10423105 RIV/00216208:11130/21:10423105

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.sapharm.2021.02.004" target="_blank" >http://dx.doi.org/10.1016/j.sapharm.2021.02.004</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.sapharm.2021.02.004" target="_blank" >10.1016/j.sapharm.2021.02.004</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Impaired awareness of hypoglycemia in a study protocol

Popis výsledku v původním jazyce

Letter: We read with interest the protocol of the SUGAR intervention study by Almomani et al. that was published recently in Research in Social and Administrative Pharmacy.1 The study aims to evaluate the effectiveness of pharmacist-led patient counselling on reducing hypoglycaemic at-tacks in older adults with type 2 diabetes mellitus. Although we agree with the most parts of the protocol outline, we would like to make one comment focused on impaired awareness of hypoglycemia (IAH) that may contribute to a further and more detailed discussion of the issue. Up to 10% of insulin-treated patients with type 2 diabetes develop IAH, which greatly increases the risk of mild and severe hypoglycemia.2 As these patients usually report any or only reduced number of hypoglycemia, we believe that the involvement of such pa-tients into the study might significantly negatively influence the study results. Thus we recommend using, for example, a method of Gold et al. to evaluate the presence and level of IAH.3 This method poses the question “do you know when your hypos are commencing?” The respondent then completes a 7-point Likert scale, with 1 representing “always aware” and 7 representing “never aware”. A score of ≥4 implies IAH, and we suggest to exclude these individuals from the study. With great respect, we suggest taking these comments into consid-eration if the study protocol will be revisited.

Název v anglickém jazyce

Impaired awareness of hypoglycemia in a study protocol

Popis výsledku anglicky

Letter: We read with interest the protocol of the SUGAR intervention study by Almomani et al. that was published recently in Research in Social and Administrative Pharmacy.1 The study aims to evaluate the effectiveness of pharmacist-led patient counselling on reducing hypoglycaemic at-tacks in older adults with type 2 diabetes mellitus. Although we agree with the most parts of the protocol outline, we would like to make one comment focused on impaired awareness of hypoglycemia (IAH) that may contribute to a further and more detailed discussion of the issue. Up to 10% of insulin-treated patients with type 2 diabetes develop IAH, which greatly increases the risk of mild and severe hypoglycemia.2 As these patients usually report any or only reduced number of hypoglycemia, we believe that the involvement of such pa-tients into the study might significantly negatively influence the study results. Thus we recommend using, for example, a method of Gold et al. to evaluate the presence and level of IAH.3 This method poses the question “do you know when your hypos are commencing?” The respondent then completes a 7-point Likert scale, with 1 representing “always aware” and 7 representing “never aware”. A score of ≥4 implies IAH, and we suggest to exclude these individuals from the study. With great respect, we suggest taking these comments into consid-eration if the study protocol will be revisited.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30304 - Public and environmental health

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

RESEARCH IN SOCIAL & ADMINISTRATIVE PHARMACY

ISSN

1551-7411

e-ISSN

1934-8150

Svazek periodika

17

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

1

Strana od-do

1447-1447

Kód UT WoS článku

000688298700021

EID výsledku v databázi Scopus

2-s2.0-85101683436