The prognostic impact of renal function decline during hospitalization for myocardial infarction

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F21%3AN0000095" target="_blank" >RIV/00064190:_____/21:N0000095 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00669806:_____/21:10423757 RIV/00216208:11140/21:10423757

Výsledek na webu

<a href="http://dx.doi.org/10.2217/cer-2020-0085" target="_blank" >http://dx.doi.org/10.2217/cer-2020-0085</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2217/cer-2020-0085" target="_blank" >10.2217/cer-2020-0085</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The prognostic impact of renal function decline during hospitalization for myocardial infarction

Popis výsledku v původním jazyce

Aim: We analyzed the mortality risk of myocardial infarction (MI) patients according to renal function, observed during hospitalization. Materials & methods: Patients hospitalized for MI between 2006 and 2018 were followed (n = 5659). We divided the sample into four groups by estimated glomerular filtration (eGFR) [ml/min]: normal functions (lowest eGFR during hospitalization >60); transiently moderate insufficiency (lowest eGFR >30 and <= 60, highest >60); permanently moderate insufficiency (highest eGFR >30 and <= 60); severe insufficiency (highest and lowest eGFR <= 30). Results: Permanently moderate renal insufficiency indicates increased 5-years all-cause mortality (hazard risk ratio: 2.27 [95% CIs: 1.87-2.75], p < 0.0001), but a similar risk was found in patients with the only transient decline of renal functions (hazard risk ratio: 2.08 [95% CIs: 1.70-2.55], p < 0.0001). Both moderate insufficiency subgroups (transient/permanent) did not statistically differ regarding mortality risk. Conclusion: Even just fluctuation of eGFR toward moderate insufficiency during hospitalization represents an important prognostic indicator in MI patients.

Název v anglickém jazyce

The prognostic impact of renal function decline during hospitalization for myocardial infarction

Popis výsledku anglicky

Aim: We analyzed the mortality risk of myocardial infarction (MI) patients according to renal function, observed during hospitalization. Materials & methods: Patients hospitalized for MI between 2006 and 2018 were followed (n = 5659). We divided the sample into four groups by estimated glomerular filtration (eGFR) [ml/min]: normal functions (lowest eGFR during hospitalization >60); transiently moderate insufficiency (lowest eGFR >30 and <= 60, highest >60); permanently moderate insufficiency (highest eGFR >30 and <= 60); severe insufficiency (highest and lowest eGFR <= 30). Results: Permanently moderate renal insufficiency indicates increased 5-years all-cause mortality (hazard risk ratio: 2.27 [95% CIs: 1.87-2.75], p < 0.0001), but a similar risk was found in patients with the only transient decline of renal functions (hazard risk ratio: 2.08 [95% CIs: 1.70-2.55], p < 0.0001). Both moderate insufficiency subgroups (transient/permanent) did not statistically differ regarding mortality risk. Conclusion: Even just fluctuation of eGFR toward moderate insufficiency during hospitalization represents an important prognostic indicator in MI patients.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH

ISSN

2042-6305

e-ISSN

2042-6313

Svazek periodika

10

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

11

Strana od-do

219-228

Kód UT WoS článku

000614756900001

EID výsledku v databázi Scopus

2-s2.0-85101127880