Common Carotid Artery Intima-media Thickness is not Increased but Distensibility is Reduced in Normotensive Patients with Type 2 Diabetes compared with Control Subjects

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F10%3A6305" target="_blank" >RIV/00064203:_____/10:6305 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/10:6305

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Common Carotid Artery Intima-media Thickness is not Increased but Distensibility is Reduced in Normotensive Patients with Type 2 Diabetes compared with Control Subjects

Popis výsledku v původním jazyce

This study evaluated carotid artery parameters in normotensive patients with type 2 diabetes compared with nondiabetic control subjects. Using a high-resolution B-mode ultrasound scanner, common carotid artery intima-media thickness (IMT) and carotid tree atheroma thickness were measured in 82 patients with type 2 diabetes and 41 controls. The distensibility of the common carotid artery was calculated using the Reneman equation. Distensibility was significantly decreased and atheroma thickness was significantly increased in the diabetes group. There was no significant difference in IMT between the two groups. Stepwise linear regression analysis revealed an association between common carotid artery distensibility and post-ischaemic dilatation of the brachial artery (a measure of endothelial function), body mass index and diabetes duration in patients with type 2 diabetes.

Název v anglickém jazyce

Common Carotid Artery Intima-media Thickness is not Increased but Distensibility is Reduced in Normotensive Patients with Type 2 Diabetes compared with Control Subjects

Popis výsledku anglicky

This study evaluated carotid artery parameters in normotensive patients with type 2 diabetes compared with nondiabetic control subjects. Using a high-resolution B-mode ultrasound scanner, common carotid artery intima-media thickness (IMT) and carotid tree atheroma thickness were measured in 82 patients with type 2 diabetes and 41 controls. The distensibility of the common carotid artery was calculated using the Reneman equation. Distensibility was significantly decreased and atheroma thickness was significantly increased in the diabetes group. There was no significant difference in IMT between the two groups. Stepwise linear regression analysis revealed an association between common carotid artery distensibility and post-ischaemic dilatation of the brachial artery (a measure of endothelial function), body mass index and diabetes duration in patients with type 2 diabetes.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

<a href="/cs/project/NR9520" target="_blank" >NR9520: Diastolická dysfunkce u diabetu mellitu 2.typu. Význam vybraných klinických, matebolických a endokrinních parametrů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of International Medical Research

ISSN

0300-0605

e-ISSN

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Svazek periodika

38

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

10

Strana od-do

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Kód UT WoS článku

000280677800013

EID výsledku v databázi Scopus

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