The association between left ventricular diastolic function and a mild-to-moderate decrease in glomerular filtration rate in patients with type 2 diabetes mellitus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F11%3A7262" target="_blank" >RIV/00064203:_____/11:7262 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/11:7262 RIV/00023761:_____/11:#0000336

Výsledek na webu

<a href="http://www.ncbi.nlm.nih.gov/pubmed/22289533" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/22289533</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The association between left ventricular diastolic function and a mild-to-moderate decrease in glomerular filtration rate in patients with type 2 diabetes mellitus

Popis výsledku v původním jazyce

This prospective study evaluated the relationship between echocardiography parameters of left ventricular (LV) diastolic function and mild-to-moderate renal function impairment in 82 patients with type 2 diabetes mellitus. The mean age of the patients was 61.1 years. A significant correlation was found between estimated glomerular filtration rate (eGFR) and the ratio of peak velocity of early transmitral flow (E) to peak velocity of early diastolic mitral annular motion (E). Cluster analysis revealed two subgroups of patients with different E values but comparable eGFRs. The correlation between eGFR and E/E was significant in 38 patients with E 7.1 cm/s, but not significant in 44 patients with E > 7.1 cm/s. The results suggest that the deterioration ofLV relaxation (E) represents the underlying condition for the association between mild-to-moderate renal function impairment and the noninvasive parameter of LV end-diastolic pressure (E/E), in patients with type 2 diabetes without any p

Název v anglickém jazyce

The association between left ventricular diastolic function and a mild-to-moderate decrease in glomerular filtration rate in patients with type 2 diabetes mellitus

Popis výsledku anglicky

This prospective study evaluated the relationship between echocardiography parameters of left ventricular (LV) diastolic function and mild-to-moderate renal function impairment in 82 patients with type 2 diabetes mellitus. The mean age of the patients was 61.1 years. A significant correlation was found between estimated glomerular filtration rate (eGFR) and the ratio of peak velocity of early transmitral flow (E) to peak velocity of early diastolic mitral annular motion (E). Cluster analysis revealed two subgroups of patients with different E values but comparable eGFRs. The correlation between eGFR and E/E was significant in 38 patients with E 7.1 cm/s, but not significant in 44 patients with E > 7.1 cm/s. The results suggest that the deterioration ofLV relaxation (E) represents the underlying condition for the association between mild-to-moderate renal function impairment and the noninvasive parameter of LV end-diastolic pressure (E/E), in patients with type 2 diabetes without any p

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

<a href="/cs/project/NR9520" target="_blank" >NR9520: Diastolická dysfunkce u diabetu mellitu 2.typu. Význam vybraných klinických, matebolických a endokrinních parametrů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of International Medical Research

ISSN

0300-0605

e-ISSN

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Svazek periodika

39

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

2178-2186

Kód UT WoS článku

000299916500014

EID výsledku v databázi Scopus

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