Crohn's disease: Is there a place for neurological screening?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F14%3A10292833" target="_blank" >RIV/00064203:_____/14:10292833 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/14:10292833

Výsledek na webu

<a href="http://dx.doi.org/10.3109/00365521.2013.867358" target="_blank" >http://dx.doi.org/10.3109/00365521.2013.867358</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3109/00365521.2013.867358" target="_blank" >10.3109/00365521.2013.867358</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Crohn's disease: Is there a place for neurological screening?

Popis výsledku v původním jazyce

Objective. Neurological complications of inflammatory bowel diseases (IBDs) are not rare but are under-diagnosed; some are probably immune-mediated. Several previous studies have suggested a higher incidence of demyelinating diseases such as multiple sclerosis in IBD patients. In this single-center, prospective, observational study, the authors focus on T2 focal white-matter lesions of the central nervous system on magnetic resonance imaging (MRI) in IBD patients that may be due to demyelination. Material and methods. A total of 70 patients with Crohn's disease were examined before beginning anti-TNF-alpha a therapy. These patients were treated with azathioprine, mesalazine or both. Patients were examined by a neurologist to detect possible signs of demyelinating disease, and patients underwent brain MRI (native T1, T2, and FLAIR sequences). Results. Thirty-seven patients (53%) exhibited abnormalities on neurological examination, and 26 patients (37%) displayed abnormalities on MRI. In

Název v anglickém jazyce

Crohn's disease: Is there a place for neurological screening?

Popis výsledku anglicky

Objective. Neurological complications of inflammatory bowel diseases (IBDs) are not rare but are under-diagnosed; some are probably immune-mediated. Several previous studies have suggested a higher incidence of demyelinating diseases such as multiple sclerosis in IBD patients. In this single-center, prospective, observational study, the authors focus on T2 focal white-matter lesions of the central nervous system on magnetic resonance imaging (MRI) in IBD patients that may be due to demyelination. Material and methods. A total of 70 patients with Crohn's disease were examined before beginning anti-TNF-alpha a therapy. These patients were treated with azathioprine, mesalazine or both. Patients were examined by a neurologist to detect possible signs of demyelinating disease, and patients underwent brain MRI (native T1, T2, and FLAIR sequences). Results. Thirty-seven patients (53%) exhibited abnormalities on neurological examination, and 26 patients (37%) displayed abnormalities on MRI. In

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Scandinavian Journal of Gastroenterology

ISSN

0036-5521

e-ISSN

—

Svazek periodika

49

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

NO - Norské království

Počet stran výsledku

4

Strana od-do

173-176

Kód UT WoS článku

000329874800006

EID výsledku v databázi Scopus

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