LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A(2) IS INCREASED IN PATIENTS WITH IMPAIRED BONE DENSITY

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F14%3A10292999" target="_blank" >RIV/00064203:_____/14:10292999 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/14:10292999

Výsledek na webu

<a href="http://dx.doi.org/10.2478/jomb-2014-0027" target="_blank" >http://dx.doi.org/10.2478/jomb-2014-0027</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2478/jomb-2014-0027" target="_blank" >10.2478/jomb-2014-0027</a>

Jazyk výsledku

angličtina

Název v původním jazyce

LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A(2) IS INCREASED IN PATIENTS WITH IMPAIRED BONE DENSITY

Popis výsledku v původním jazyce

Background: Increased levels of lipoprotein-associated phospholipase A(2) are associated with atherosclerosis, and may contribute to cardiac disease. The aim of this study was to analyze serum levels of lipoprotein phospholipase A(2) (Lp-PLA(2)) in patients with impaired bone resorption and correlate the findings with markers of bone metabolism (osteocalcin) and other biochemical markers (cholesterol, low density lipoprotein, triacylglycerols). Methods: Serum Lp-PLA(2) was measured by a turbidimetric method in a group of currently treated 85 patients with impaired bone resorption and in a control group of 46 healthy individuals. Serum triacylglycerols was measured by the electrochemiluminescence immunoassay. Cholesterol, low density lipoprotein and triacylglycerols were measured by commercially available enzymatic assays. Bone density was investigated by dual energy X-ray densitometry performed on the lower spine and hips. Results: Concentrations of LP-PLA(2) were significantly elevate

Název v anglickém jazyce

LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A(2) IS INCREASED IN PATIENTS WITH IMPAIRED BONE DENSITY

Popis výsledku anglicky

Background: Increased levels of lipoprotein-associated phospholipase A(2) are associated with atherosclerosis, and may contribute to cardiac disease. The aim of this study was to analyze serum levels of lipoprotein phospholipase A(2) (Lp-PLA(2)) in patients with impaired bone resorption and correlate the findings with markers of bone metabolism (osteocalcin) and other biochemical markers (cholesterol, low density lipoprotein, triacylglycerols). Methods: Serum Lp-PLA(2) was measured by a turbidimetric method in a group of currently treated 85 patients with impaired bone resorption and in a control group of 46 healthy individuals. Serum triacylglycerols was measured by the electrochemiluminescence immunoassay. Cholesterol, low density lipoprotein and triacylglycerols were measured by commercially available enzymatic assays. Bone density was investigated by dual energy X-ray densitometry performed on the lower spine and hips. Results: Concentrations of LP-PLA(2) were significantly elevate

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Medical Biochemistry

ISSN

1452-8258

e-ISSN

—

Svazek periodika

33

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

RS - Srbská republika

Počet stran výsledku

6

Strana od-do

317-322

Kód UT WoS článku

000340863100003

EID výsledku v databázi Scopus

—