Application of a Scale for the Assessment and Rating of Ataxia (SARA) in Friedreich's ataxia patients according to posturography is limited

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F14%3A10293005" target="_blank" >RIV/00064203:_____/14:10293005 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/14:10293005 RIV/00216208:11510/14:10293612 RIV/00159816:_____/14:00061068

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jns.2014.04.001" target="_blank" >http://dx.doi.org/10.1016/j.jns.2014.04.001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jns.2014.04.001" target="_blank" >10.1016/j.jns.2014.04.001</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Application of a Scale for the Assessment and Rating of Ataxia (SARA) in Friedreich's ataxia patients according to posturography is limited

Popis výsledku v původním jazyce

Background: A scale for the Assessment and Rating of Ataxia (SARA) was developed for evaluation of autosomal dominant cerebellar ataxias (ADCA) and was also recommended for clinical trials of Friedreich's ataxia patients (FRDA). FRDA, unlike ADCA, is characterized as being a sensory type of ataxia for which the disease-specific Friedreich ataxia rating scale (FARS) was developed. The objective of this study was to determine whether SARA and FARS scores are associated with posturographic parameters in FRDA patients. Method: Adult patients with genetically confirmed FRDA (n = 11) and ADCA (n = 13) were evaluated by SARA, FARS and posturography. Results: FRDA patients' postural stability parameters, in stance with visual control, correlated with balance impairment in FARS (r = 0.622; p < 0.05) and SARA (r = 0.735; p < 0.05). Without visual control, only FARS correlated with balance impairment (r = 0.732; p < 0.05). Conclusion: The SARA, in FRDA patients, correlates with stance with visual

Název v anglickém jazyce

Application of a Scale for the Assessment and Rating of Ataxia (SARA) in Friedreich's ataxia patients according to posturography is limited

Popis výsledku anglicky

Background: A scale for the Assessment and Rating of Ataxia (SARA) was developed for evaluation of autosomal dominant cerebellar ataxias (ADCA) and was also recommended for clinical trials of Friedreich's ataxia patients (FRDA). FRDA, unlike ADCA, is characterized as being a sensory type of ataxia for which the disease-specific Friedreich ataxia rating scale (FARS) was developed. The objective of this study was to determine whether SARA and FARS scores are associated with posturographic parameters in FRDA patients. Method: Adult patients with genetically confirmed FRDA (n = 11) and ADCA (n = 13) were evaluated by SARA, FARS and posturography. Results: FRDA patients' postural stability parameters, in stance with visual control, correlated with balance impairment in FARS (r = 0.622; p < 0.05) and SARA (r = 0.735; p < 0.05). Without visual control, only FARS correlated with balance impairment (r = 0.732; p < 0.05). Conclusion: The SARA, in FRDA patients, correlates with stance with visual

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of the Neurological Sciences

ISSN

0022-510X

e-ISSN

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Svazek periodika

341

Číslo periodika v rámci svazku

1-2

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

4

Strana od-do

64-67

Kód UT WoS článku

000337262200014

EID výsledku v databázi Scopus

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